Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/3442/gene/?format=api
{ "data": { "type": "Gene", "id": "SQSTM1", "attributes": { "go_molecular_function": [ "['protein kinase C binding', 'zinc ion binding', 'ubiquitin protein ligase binding', 'ubiquitin binding', 'enzyme binding', 'protein kinase binding', 'protein binding', 'K63-linked polyubiquitin modification-dependent protein binding', 'receptor tyrosine kinase binding', 'ionotropic glutamate receptor binding', 'protein serine/threonine kinase activity', 'SH2 domain binding', 'identical protein binding', 'protein-containing complex binding']" ], "pathway_id": [ "kegg_path:hsa04137", "kegg_path:hsa04140", "kegg_path:hsa04217", "kegg_path:hsa04218", "kegg_path:hsa04380", "kegg_path:hsa05014", "kegg_path:hsa05022", "kegg_path:hsa05131", "kegg_path:hsa05418", "R-HSA-1280215", "R-HSA-162582", "R-HSA-1632852", "R-HSA-168256", "R-HSA-193639", "R-HSA-193704", "R-HSA-204998", "R-HSA-205043", "R-HSA-209543", "R-HSA-209560", "R-HSA-446652", "R-HSA-449147", "R-HSA-5205647", "R-HSA-5205685", "R-HSA-73887", "R-HSA-9020702", "R-HSA-9612973", "R-HSA-9663891", "R-HSA-9664873" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "Q13501", "ensembl_id": "None", "entrez_id": "ENSG00000161011", "chromosome_number": "5" }, "relationships": { "variant_set": { "meta": { "count": 13 }, "data": [ { "type": "SmallVariant", "id": "43" }, { "type": "SmallVariant", "id": "531" }, { "type": "SmallVariant", "id": "534" }, { "type": "SmallVariant", "id": "938" }, { "type": "SmallVariant", "id": "1378" }, { "type": "SmallVariant", "id": "1807" }, { "type": "SmallVariant", "id": "1809" }, { "type": "SmallVariant", "id": "2058" }, { "type": "SmallVariant", "id": "2926" }, { "type": "SmallVariant", "id": "2938" }, { "type": "SmallVariant", "id": "3420" }, { "type": "SmallVariant", "id": "3442" }, { "type": "SmallVariant", "id": "3604" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SQSTM1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SQSTM1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 12 }, "data": [ { "type": "GeneCombination", "id": "18" }, { "type": "GeneCombination", "id": "176" }, { "type": "GeneCombination", "id": "179" }, { "type": "GeneCombination", "id": "271" }, { "type": "GeneCombination", "id": "298" }, { "type": "GeneCombination", "id": "597" }, { "type": "GeneCombination", "id": "709" }, { "type": "GeneCombination", "id": "972" }, { "type": "GeneCombination", "id": "977" }, { "type": "GeneCombination", "id": "1005" }, { "type": "GeneCombination", "id": "1152" }, { "type": "GeneCombination", "id": "1156" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SQSTM1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SQSTM1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SQSTM1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.640390", "status": "CU", "curator": null, "submitter": "cnachteg" } }