Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/SQSTM1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "18", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:45.899516" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI022" }, { "type": "Combination", "id": "OLI1732" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/18/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/18/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SQSTM1" }, { "type": "Gene", "id": "TIA1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/18/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/18/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/18/?format=api" } }, { "type": "GeneCombination", "id": "176", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Autophagy - animal" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:53.966846" }, "relationships": { "combination_set": { "meta": { "count": 4 }, "data": [ { "type": "Combination", "id": "OLI272" }, { "type": "Combination", "id": "OLI633" }, { "type": "Combination", "id": "OLI823" }, { "type": "Combination", "id": "OLI1623" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/176/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/176/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "C9orf72" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/176/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/176/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/176/?format=api" } }, { "type": "GeneCombination", "id": "179", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:00:54.041954" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI275" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/179/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/179/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ATXN2" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/179/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/179/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/179/?format=api" } }, { "type": "GeneCombination", "id": "271", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(SQSTM1, TARDBP)" ], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.785959" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI404" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/271/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/271/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SQSTM1" }, { "type": "Gene", "id": "TARDBP" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/271/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/271/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/271/?format=api" } }, { "type": "GeneCombination", "id": "298", "attributes": { "gene_relationship": [ "Involved in the same disease", "Directly interacting", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [ "(SOD1, SQSTM1)" ], "common_pathways": [ "Signaling by Interleukins", "Immune System", "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis", "Cytokine Signaling in Immune system" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:01.098760" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI440" }, { "type": "Combination", "id": "OLI636" }, { "type": "Combination", "id": "OLI1700" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/298/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/298/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SOD1" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/298/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/298/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/298/?format=api" } }, { "type": "GeneCombination", "id": "597", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis", "Pathways of neurodegeneration - multiple diseases" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:18.117464" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI824" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/597/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/597/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SIGMAR1" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/597/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/597/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/597/?format=api" } }, { "type": "GeneCombination", "id": "709", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:01.122384" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI952" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/709/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/709/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DAO" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/709/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/709/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/709/?format=api" } }, { "type": "GeneCombination", "id": "972", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.283573" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1394" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/972/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/972/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "POLR3B" }, { "type": "Gene", "id": "SMCHD1" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/972/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/972/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/972/?format=api" } }, { "type": "GeneCombination", "id": "977", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.311430" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1400" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/977/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/977/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "KISS1R" }, { "type": "Gene", "id": "PNPLA6" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/977/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/977/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/977/?format=api" } }, { "type": "GeneCombination", "id": "1005", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.468095" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1430" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1005/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1005/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1005/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1005/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1005/?format=api" } }, { "type": "GeneCombination", "id": "1152", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Pathways of neurodegeneration - multiple diseases", "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.407346" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1632" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1152/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1152/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PRPH" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1152/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1152/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1152/?format=api" } }, { "type": "GeneCombination", "id": "1156", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Amyotrophic lateral sclerosis" ], "genecomb_metascore": 2, "lastmodified": "2024-02-29T15:02:21.482005" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1637" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1156/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1156/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SETX" }, { "type": "Gene", "id": "SQSTM1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1156/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1156/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1156/?format=api" } } ] }