Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/2541/gene/?format=api
{ "data": { "type": "Gene", "id": "STUB1", "attributes": { "go_molecular_function": [ "['ubiquitin-protein transferase activity', 'chaperone binding', 'ubiquitin-ubiquitin ligase activity', 'Hsp90 protein binding', 'TPR domain binding', 'enzyme binding', 'heat shock protein binding', 'kinase binding', 'Hsp70 protein binding', 'G protein-coupled receptor binding', 'protein binding', 'SMAD binding', 'protein-macromolecule adaptor activity', 'tau protein binding', 'protein homodimerization activity', 'ubiquitin protein ligase binding', 'ubiquitin protein ligase activity', 'misfolded protein binding']" ], "pathway_id": [ "kegg_path:hsa04120", "kegg_path:hsa04141", "R-HSA-1227986", "R-HSA-1257604", "R-HSA-1280218", "R-HSA-162582", "R-HSA-168256", "R-HSA-170834", "R-HSA-212436", "R-HSA-2173788", "R-HSA-2173789", "R-HSA-5213460", "R-HSA-5218859", "R-HSA-5357801", "R-HSA-5675482", "R-HSA-6807070", "R-HSA-73857", "R-HSA-74160", "R-HSA-8863795", "R-HSA-8878166", "R-HSA-8939902", "R-HSA-8948751", "R-HSA-9006925", "R-HSA-9006934", "R-HSA-9006936", "R-HSA-983168", "R-HSA-983169" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q9UNE7", "ensembl_id": "None", "entrez_id": "ENSG00000103266", "chromosome_number": "16" }, "relationships": { "variant_set": { "meta": { "count": 30 }, "data": [ { "type": "SmallVariant", "id": "2525" }, { "type": "SmallVariant", "id": "2527" }, { "type": "SmallVariant", "id": "2529" }, { "type": "SmallVariant", "id": "2531" }, { "type": "SmallVariant", "id": "2533" }, { "type": "SmallVariant", "id": "2534" }, { "type": "SmallVariant", "id": "2536" }, { "type": "SmallVariant", "id": "2537" }, { "type": "SmallVariant", "id": "2538" }, { "type": "SmallVariant", "id": "2539" }, { "type": "SmallVariant", "id": "2541" }, { "type": "SmallVariant", "id": "2542" }, { "type": "SmallVariant", "id": "2544" }, { "type": "SmallVariant", "id": "2545" }, { "type": "SmallVariant", "id": "2547" }, { "type": "SmallVariant", "id": "2548" }, { "type": "SmallVariant", "id": "2551" }, { "type": "SmallVariant", "id": "2554" }, { "type": "SmallVariant", "id": "2555" }, { "type": "SmallVariant", "id": "2558" }, { "type": "SmallVariant", "id": "2560" }, { "type": "SmallVariant", "id": "2561" }, { "type": "SmallVariant", "id": "2563" }, { "type": "SmallVariant", "id": "2565" }, { "type": "SmallVariant", "id": "2566" }, { "type": "SmallVariant", "id": "2568" }, { "type": "SmallVariant", "id": "2570" }, { "type": "SmallVariant", "id": "2572" }, { "type": "SmallVariant", "id": "2573" }, { "type": "SmallVariant", "id": "2574" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/STUB1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/STUB1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "857" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/STUB1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/STUB1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/STUB1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2022-05-12T19:42:22.255857", "status": "CU", "curator": null, "submitter": "cnachteg" } }