Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/1388/gene/?format=api
{ "data": { "type": "Gene", "id": "TBK1", "attributes": { "go_molecular_function": [ "['nucleic acid binding', 'protein serine/threonine/tyrosine kinase activity', 'protein binding', 'protein kinase activity', 'protein phosphatase binding', 'phosphoprotein binding', 'protein serine/threonine kinase activity', 'protein serine kinase activity', 'identical protein binding', 'ATP binding']" ], "pathway_id": [ "kegg_path:hsa04014", "kegg_path:hsa04137", "kegg_path:hsa04140", "kegg_path:hsa04620", "kegg_path:hsa04621", "kegg_path:hsa04622", "kegg_path:hsa04623", "kegg_path:hsa04657", "kegg_path:hsa05014", "kegg_path:hsa05022", "kegg_path:hsa05131", "kegg_path:hsa05135", "kegg_path:hsa05160", "kegg_path:hsa05161", "kegg_path:hsa05162", "kegg_path:hsa05163", "kegg_path:hsa05164", "kegg_path:hsa05165", "kegg_path:hsa05167", "kegg_path:hsa05168", "kegg_path:hsa05169", "kegg_path:hsa05170", "kegg_path:hsa05171", "R-HSA-1280215", "R-HSA-1606322", "R-HSA-1606341", "R-HSA-1643685", "R-HSA-166016", "R-HSA-166166", "R-HSA-168164", "R-HSA-168249", "R-HSA-168256", "R-HSA-168898", "R-HSA-168928", "R-HSA-1834941", "R-HSA-1834949", "R-HSA-3134975", "R-HSA-3249367", "R-HSA-3270619", "R-HSA-446652", "R-HSA-449147", "R-HSA-5663205", "R-HSA-9008059", "R-HSA-9013973", "R-HSA-918233", "R-HSA-933541", "R-HSA-936440", "R-HSA-936964", "R-HSA-937061", "R-HSA-9679191", "R-HSA-9679506" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "Q9UHD2", "ensembl_id": "None", "entrez_id": "ENSG00000183735", "chromosome_number": "12" }, "relationships": { "variant_set": { "meta": { "count": 10 }, "data": [ { "type": "SmallVariant", "id": "790" }, { "type": "SmallVariant", "id": "1388" }, { "type": "SmallVariant", "id": "1390" }, { "type": "SmallVariant", "id": "1392" }, { "type": "SmallVariant", "id": "1813" }, { "type": "SmallVariant", "id": "3419" }, { "type": "SmallVariant", "id": "3421" }, { "type": "SmallVariant", "id": "3424" }, { "type": "SmallVariant", "id": "3602" }, { "type": "SmallVariant", "id": "3644" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TBK1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TBK1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "248" }, { "type": "GeneCombination", "id": "438" }, { "type": "GeneCombination", "id": "599" }, { "type": "GeneCombination", "id": "1147" }, { "type": "GeneCombination", "id": "1212" }, { "type": "GeneCombination", "id": "1227" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TBK1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TBK1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TBK1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.559222", "status": "CU", "curator": null, "submitter": "cnachteg" } }