Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/1269/gene/?format=api
{ "data": { "type": "Gene", "id": "CYP1A1", "attributes": { "go_molecular_function": [ "oxygen binding", "lyase activity", "hydroperoxy icosatetraenoate dehydratase activity", "aromatase activity", "metal ion binding", "monooxygenase activity", "oxidoreductase activity" ], "pathway_id": [ "kegg_path:hsa04913", "kegg_path:hsa04913", "R-HSA-8978868", "R-HSA-2142670", "R-HSA-1430728", "R-HSA-2142816", "R-HSA-9018677", "kegg_path:hsa05204", "kegg_path:hsa05204", "R-HSA-1989781", "R-HSA-211859", "kegg_path:hsa00380", "kegg_path:hsa00380", "R-HSA-211897", "R-HSA-211945", "kegg_path:hsa00140", "kegg_path:hsa01100", "kegg_path:hsa00140", "kegg_path:hsa01100", "R-HSA-556833", "R-HSA-9018681", "kegg_path:hsa00830", "kegg_path:hsa00830", "R-HSA-211981", "R-HSA-2142753", "R-HSA-9018678", "kegg_path:hsa00980", "kegg_path:hsa00980", "R-HSA-400206" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "P04798", "ensembl_id": "ENSG00000140465", "entrez_id": "1543", "chromosome_number": "15" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "738" }, { "type": "SmallVariant", "id": "743" }, { "type": "SmallVariant", "id": "1269" }, { "type": "SmallVariant", "id": "1296" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CYP1A1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CYP1A1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "236" }, { "type": "GeneCombination", "id": "237" }, { "type": "GeneCombination", "id": "405" }, { "type": "GeneCombination", "id": "410" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CYP1A1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CYP1A1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CYP1A1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.968652", "status": "CU", "curator": null, "submitter": "cnachteg" } }