Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/1253/gene/?format=api
{ "data": { "type": "Gene", "id": "DUOX2", "attributes": { "go_molecular_function": [ "['heme binding', 'NADPH oxidase H202-forming activity', 'NADH oxidase H202-forming activity', 'calcium ion binding', 'peroxidase activity', 'NAD(P)H oxidase H2O2-forming activity', 'protein binding', 'superoxide-generating NAD(P)H oxidase activity']" ], "pathway_id": [ "kegg_path:hsa04918", "R-HSA-1430728", "R-HSA-209776", "R-HSA-209968", "R-HSA-71291" ], "essential_gene": "Non-essential", "status": null, "uniprot_acc": "Q9NRD8", "ensembl_id": "None", "entrez_id": "ENSG00000140279", "chromosome_number": "15" }, "relationships": { "variant_set": { "meta": { "count": 52 }, "data": [ { "type": "SmallVariant", "id": "68" }, { "type": "SmallVariant", "id": "69" }, { "type": "SmallVariant", "id": "84" }, { "type": "SmallVariant", "id": "996" }, { "type": "SmallVariant", "id": "1002" }, { "type": "SmallVariant", "id": "1005" }, { "type": "SmallVariant", "id": "1011" }, { "type": "SmallVariant", "id": "1012" }, { "type": "SmallVariant", "id": "1018" }, { "type": "SmallVariant", "id": "1020" }, { "type": "SmallVariant", "id": "1021" }, { "type": "SmallVariant", "id": "1097" }, { "type": "SmallVariant", "id": "1098" }, { "type": "SmallVariant", "id": "1172" }, { "type": "SmallVariant", "id": "1174" }, { "type": "SmallVariant", "id": "1176" }, { "type": "SmallVariant", "id": "1178" }, { "type": "SmallVariant", "id": "1179" }, { "type": "SmallVariant", "id": "1180" }, { "type": "SmallVariant", "id": "1184" }, { "type": "SmallVariant", "id": "1234" }, { "type": "SmallVariant", "id": "1252" }, { "type": "SmallVariant", "id": "1253" }, { "type": "SmallVariant", "id": "1256" }, { "type": "SmallVariant", "id": "1261" }, { "type": "SmallVariant", "id": "1262" }, { "type": "SmallVariant", "id": "1263" }, { "type": "SmallVariant", "id": "2143" }, { "type": "SmallVariant", "id": "2145" }, { "type": "SmallVariant", "id": "2147" }, { "type": "SmallVariant", "id": "2149" }, { "type": "SmallVariant", "id": "2152" }, { "type": "SmallVariant", "id": "2208" }, { "type": "SmallVariant", "id": "2210" }, { "type": "SmallVariant", "id": "2212" }, { "type": "SmallVariant", "id": "2214" }, { "type": "SmallVariant", "id": "2216" }, { "type": "SmallVariant", "id": "2349" }, { "type": "SmallVariant", "id": "2359" }, { "type": "SmallVariant", "id": "2362" }, { "type": "SmallVariant", "id": "2371" }, { "type": "SmallVariant", "id": "2373" }, { "type": "SmallVariant", "id": "2523" }, { "type": "SmallVariant", "id": "2524" }, { "type": "SmallVariant", "id": "3123" }, { "type": "SmallVariant", "id": "3128" }, { "type": "SmallVariant", "id": "3132" }, { "type": "SmallVariant", "id": "3133" }, { "type": "SmallVariant", "id": "3144" }, { "type": "SmallVariant", "id": "3774" }, { "type": "SmallVariant", "id": "3775" }, { "type": "SmallVariant", "id": "3776" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DUOX2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DUOX2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 22 }, "data": [ { "type": "GeneCombination", "id": "26" }, { "type": "GeneCombination", "id": "27" }, { "type": "GeneCombination", "id": "319" }, { "type": "GeneCombination", "id": "321" }, { "type": "GeneCombination", "id": "323" }, { "type": "GeneCombination", "id": "378" }, { "type": "GeneCombination", "id": "394" }, { "type": "GeneCombination", "id": "400" }, { "type": "GeneCombination", "id": "402" }, { "type": "GeneCombination", "id": "797" }, { "type": "GeneCombination", "id": "794" }, { "type": "GeneCombination", "id": "803" }, { "type": "GeneCombination", "id": "804" }, { "type": "GeneCombination", "id": "795" }, { "type": "GeneCombination", "id": "359" }, { "type": "GeneCombination", "id": "1045" }, { "type": "GeneCombination", "id": "1046" }, { "type": "GeneCombination", "id": "1047" }, { "type": "GeneCombination", "id": "1051" }, { "type": "GeneCombination", "id": "798" }, { "type": "GeneCombination", "id": "799" }, { "type": "GeneCombination", "id": "800" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DUOX2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DUOX2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DUOX2/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.392952", "status": "CU", "curator": null, "submitter": "cnachteg" } }