Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/DUOX2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "26", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Metabolism of amine-derived hormones", "Thyroxine biosynthesis", "Thyroid hormone synthesis", "Metabolism of amino acids and derivatives" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:46.216302" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI031" }, { "type": "Combination", "id": "OLI468" }, { "type": "Combination", "id": "OLI474" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/26/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/26/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "TG" }, { "type": "Gene", "id": "TPO" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/26/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/26/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/26/?format=api" } }, { "type": "GeneCombination", "id": "27", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype", "Monogenic experiments only", "Same pathway", "Similar function" ], "protein_interactions": [], "common_pathways": [ "Metabolism of amine-derived hormones", "Thyroxine biosynthesis", "Metabolism of amino acids and derivatives" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:46.246270" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI032" }, { "type": "Combination", "id": "OLI040" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/27/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/27/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX1" }, { "type": "Gene", "id": "DUOX2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/27/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/27/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/27/?format=api" } }, { "type": "GeneCombination", "id": "319", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Thyroid hormone synthesis" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:02.148640" }, "relationships": { "combination_set": { "meta": { "count": 4 }, "data": [ { "type": "Combination", "id": "OLI465" }, { "type": "Combination", "id": "OLI473" }, { "type": "Combination", "id": "OLI590" }, { "type": "Combination", "id": "OLI592" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/319/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/319/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "SLC26A4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/319/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/319/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/319/?format=api" } }, { "type": "GeneCombination", "id": "321", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Thyroid hormone synthesis" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:02.228383" }, "relationships": { "combination_set": { "meta": { "count": 13 }, "data": [ { "type": "Combination", "id": "OLI467" }, { "type": "Combination", "id": "OLI563" }, { "type": "Combination", "id": "OLI564" }, { "type": "Combination", "id": "OLI565" }, { "type": "Combination", "id": "OLI567" }, { "type": "Combination", "id": "OLI989" }, { "type": "Combination", "id": "OLI990" }, { "type": "Combination", "id": "OLI1021" }, { "type": "Combination", "id": "OLI1022" }, { "type": "Combination", "id": "OLI1023" }, { "type": "Combination", "id": "OLI1024" }, { "type": "Combination", "id": "OLI1807" }, { "type": "Combination", "id": "OLI1808" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/321/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/321/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "TG" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/321/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/321/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/321/?format=api" } }, { "type": "GeneCombination", "id": "323", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Thyroid hormone synthesis" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:02.396530" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI470" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/323/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/323/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "DUOXA2" }, { "type": "Gene", "id": "TG" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/323/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/323/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/323/?format=api" } }, { "type": "GeneCombination", "id": "378", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:05.248125" }, "relationships": { "combination_set": { "meta": { "count": 4 }, "data": [ { "type": "Combination", "id": "OLI562" }, { "type": "Combination", "id": "OLI991" }, { "type": "Combination", "id": "OLI992" }, { "type": "Combination", "id": "OLI1804" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/378/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/378/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "DUOXA2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/378/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/378/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/378/?format=api" } }, { "type": "GeneCombination", "id": "394", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:06.118930" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI583" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/394/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/394/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "GLIS3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/394/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/394/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/394/?format=api" } }, { "type": "GeneCombination", "id": "400", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Thyroid hormone synthesis" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:06.415347" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI591" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/400/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/400/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "PAX8" }, { "type": "Gene", "id": "SLC26A4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/400/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/400/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/400/?format=api" } }, { "type": "GeneCombination", "id": "402", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Metabolism of amine-derived hormones", "Thyroxine biosynthesis", "Metabolism of amino acids and derivatives", "Thyroid hormone synthesis" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:06.545418" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI594" }, { "type": "Combination", "id": "OLI1020" }, { "type": "Combination", "id": "OLI1805" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/402/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/402/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "TPO" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/402/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/402/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/402/?format=api" } }, { "type": "GeneCombination", "id": "797", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.768680" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1080" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/797/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/797/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CDCA8" }, { "type": "Gene", "id": "DUOX2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/797/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/797/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/797/?format=api" } }, { "type": "GeneCombination", "id": "794", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.753871" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1077" }, { "type": "Combination", "id": "OLI1496" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/794/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/794/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "DUOXA1" }, { "type": "Gene", "id": "GLIS3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/794/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/794/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/794/?format=api" } }, { "type": "GeneCombination", "id": "803", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.806474" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1088" }, { "type": "Combination", "id": "OLI1504" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/803/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/803/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "HOXB3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/803/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/803/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/803/?format=api" } }, { "type": "GeneCombination", "id": "804", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.810718" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1089" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/804/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/804/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "EYA1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/804/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/804/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/804/?format=api" } }, { "type": "GeneCombination", "id": "795", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-03-01T14:47:17.298752" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1078" }, { "type": "Combination", "id": "OLI1497" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/795/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/795/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "DUOXA1" }, { "type": "Gene", "id": "JAG1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/795/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/795/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/795/?format=api" } }, { "type": "GeneCombination", "id": "359", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Thyroid hormone synthesis" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.697101" }, "relationships": { "combination_set": { "meta": { "count": 13 }, "data": [ { "type": "Combination", "id": "OLI518" }, { "type": "Combination", "id": "OLI986" }, { "type": "Combination", "id": "OLI987" }, { "type": "Combination", "id": "OLI988" }, { "type": "Combination", "id": "OLI1074" }, { "type": "Combination", "id": "OLI1076" }, { "type": "Combination", "id": "OLI1175" }, { "type": "Combination", "id": "OLI1481" }, { "type": "Combination", "id": "OLI1482" }, { "type": "Combination", "id": "OLI1483" }, { "type": "Combination", "id": "OLI1485" }, { "type": "Combination", "id": "OLI1494" }, { "type": "Combination", "id": "OLI1806" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/359/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/359/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "TSHR" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/359/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/359/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/359/?format=api" } }, { "type": "GeneCombination", "id": "1045", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.703434" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1484" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1045/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1045/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "DUOXA1" }, { "type": "Gene", "id": "FOXE1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1045/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1045/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1045/?format=api" } }, { "type": "GeneCombination", "id": "1046", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.713438" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1486" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1046/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1046/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "DUOXA2" }, { "type": "Gene", "id": "GLIS3" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1046/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1046/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1046/?format=api" } }, { "type": "GeneCombination", "id": "1047", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.717866" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1487" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1047/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1047/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "DUOX2" }, { "type": "Gene", "id": "SHH" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1047/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1047/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1047/?format=api" } }, { "type": "GeneCombination", "id": "1051", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Metabolism", "Metabolism of amino acids and derivatives" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.734863" }, "relationships": { "combination_set": { "meta": { 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