Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/TACR3/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "262", "attributes": { "gene_relationship": [ "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.373759" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI393" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/262/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/262/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SPRY4" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/262/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/262/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/262/?format=api" } }, { "type": "GeneCombination", "id": "264", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.446083" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI395" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/264/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/264/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ANOS1" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/264/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/264/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/264/?format=api" } }, { "type": "GeneCombination", "id": "258", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Calcium signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:26.793521" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI374" }, { "type": "Combination", "id": "OLI392" }, { "type": "Combination", "id": "OLI1290" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/258/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/258/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FGFR1" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/258/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/258/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/258/?format=api" } }, { "type": "GeneCombination", "id": "355", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:03.796881" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI512" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/355/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/355/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NSMF" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/355/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/355/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/355/?format=api" } }, { "type": "GeneCombination", "id": "620", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Calcium signaling pathway", "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:19.148265" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI853" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/620/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/620/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "ANOS1" }, { "type": "Gene", "id": "NOS1" }, { "type": "Gene", "id": "STS" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/620/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/620/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/620/?format=api" } }, { "type": "GeneCombination", "id": "896", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "GPCR ligand binding", "GPCR downstream signalling", "Signal Transduction", "Peptide ligand-binding receptors", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.754417" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1278" }, { "type": "Combination", "id": "OLI1289" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/896/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/896/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/896/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/896/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/896/?format=api" } }, { "type": "GeneCombination", "id": "897", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.758690" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1279" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/897/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/897/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "FLRT3" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/897/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/897/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/897/?format=api" } }, { "type": "GeneCombination", "id": "899", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.771697" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1282" }, { "type": "Combination", "id": "OLI1283" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/899/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/899/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/899/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/899/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/899/?format=api" } }, { "type": "GeneCombination", "id": "973", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.287884" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1395" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/973/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/973/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "IGSF10" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/973/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/973/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/973/?format=api" } }, { "type": "GeneCombination", "id": "1133", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [ "(TAC3, TACR3)" ], "common_pathways": [ "GPCR ligand binding", "Neuroactive ligand-receptor interaction", "GPCR downstream signalling", "Signal Transduction", "Peptide ligand-binding receptors", "Class A/1 (Rhodopsin-like receptors)", "Tachykinin receptors bind tachykinins", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:28.482257" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1602" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1133/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1133/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "TAC3" }, { "type": "Gene", "id": "TACR3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1133/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1133/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1133/?format=api" } } ] }