Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/SCN5A/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "123", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:51.165672" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI183" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/123/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/123/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "SCN5A" }, { "type": "Gene", "id": "TRPM4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/123/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/123/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/123/?format=api" } }, { "type": "GeneCombination", "id": "134", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway", "Monogenic experiments only" ], "protein_interactions": [], "common_pathways": [ "Muscle contraction", "Cardiac conduction", "Adrenergic signaling in cardiomyocytes" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:51.715512" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI202" }, { "type": "Combination", "id": "OLI445" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/134/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/134/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "KCNQ1" }, { "type": "Gene", "id": "SCN5A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/134/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/134/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/134/?format=api" } }, { "type": "GeneCombination", "id": "249", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway", "Same protein complex" ], "protein_interactions": [], "common_pathways": [ "Muscle contraction", "Cardiac conduction" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:58.325029" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI363" }, { "type": "Combination", "id": "OLI985" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/249/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/249/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "KCNH2" }, { "type": "Gene", "id": "SCN5A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/249/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/249/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/249/?format=api" } }, { "type": "GeneCombination", "id": "250", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cardiac conduction" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:58.359750" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI364" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/250/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/250/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "KCNE2" }, { "type": "Gene", "id": "SCN5A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/250/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/250/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/250/?format=api" } }, { "type": "GeneCombination", "id": "439", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Nervous system development", "Phase 0 - rapid depolarisation", "Muscle contraction", "Axon guidance", "Cardiac conduction", "Adrenergic signaling in cardiomyocytes" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:08.973758" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI645" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/439/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/439/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CACNA1C" }, { "type": "Gene", "id": "SCN5A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/439/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/439/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/439/?format=api" } }, { "type": "GeneCombination", "id": "862", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Muscle contraction", "Adrenergic signaling in cardiomyocytes", "Cardiac conduction" ], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:50:05.794335" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1227" }, { "type": "Combination", "id": "OLI1228" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/862/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/862/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "KCNE1" }, { "type": "Gene", "id": "SCN5A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/862/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/862/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/862/?format=api" } } ] }