Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/RYR2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "441", "attributes": { "gene_relationship": [ "Indirectly interacting", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(CACNA1C, RYR2)" ], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:09.166666" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI647" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/441/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/441/combinations/?format=api" } }, "genes": { "meta": { "count": 8 }, "data": [ { "type": "Gene", "id": "AKAP9" }, { "type": "Gene", "id": "CACNA1C" }, { "type": "Gene", "id": "DSC2" }, { "type": "Gene", "id": "OBSCN" }, { "type": "Gene", "id": "RBM20" }, { "type": "Gene", "id": "RYR2" }, { "type": "Gene", "id": "TECRL" }, { "type": "Gene", "id": "VCL" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/441/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/441/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/441/?format=api" } }, { "type": "GeneCombination", "id": "732", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:56:08.392564" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI981" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/732/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/732/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "GJA5" }, { "type": "Gene", "id": "RYR2" }, { "type": "Gene", "id": "TNNI3K" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/732/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/732/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/732/?format=api" } }, { "type": "GeneCombination", "id": "1031", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.598052" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1463" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1031/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1031/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "RELN" }, { "type": "Gene", "id": "RYR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1031/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1031/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1031/?format=api" } } ] }