Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/PROK2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "133", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:51.668939" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI201" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/133/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/133/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "GNRHR" }, { "type": "Gene", "id": "PROK2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/133/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/133/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/133/?format=api" } }, { "type": "GeneCombination", "id": "190", "attributes": { "gene_relationship": [ "Involved in the same disease", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:00:54.436793" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI287" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/190/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/190/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROK2" }, { "type": "Gene", "id": "SEMA3A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/190/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/190/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/190/?format=api" } }, { "type": "GeneCombination", "id": "265", "attributes": { "gene_relationship": [ "Directly interacting", "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "GPCR ligand binding", "GPCR downstream signalling", "Signal Transduction", "Peptide ligand-binding receptors", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "G alpha (q) signalling events" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.074784" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI396" }, { "type": "Combination", "id": "OLI834" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/265/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/265/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "PROK2" }, { "type": "Gene", "id": "PROKR2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/265/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/265/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/265/?format=api" } }, { "type": "GeneCombination", "id": "906", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.821848" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1297" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/906/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/906/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "PROK2" }, { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "SEMA3A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/906/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/906/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/906/?format=api" } }, { "type": "GeneCombination", "id": "991", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.390211" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1414" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/991/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/991/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "OTUD4" }, { "type": "Gene", "id": "PROK2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/991/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/991/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/991/?format=api" } }, { "type": "GeneCombination", "id": "1101", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:28.205018" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1557" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1101/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1101/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "HSD17B6" }, { "type": "Gene", "id": "NR5A1" }, { "type": "Gene", "id": "PROK2" }, { "type": "Gene", "id": "SEMA3F" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1101/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1101/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1101/?format=api" } }, { "type": "GeneCombination", "id": "1165", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-02-29T15:02:21.658142" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1651" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1165/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1165/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "CHD7" }, { "type": "Gene", "id": "PROK2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1165/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1165/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1165/?format=api" } } ] }