GET

Gene Combination List

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/PLXNA1/genecombinations/?format=api
HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "246",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:00:58.127556"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI358"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/246/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/246/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        },
                        {
                            "type": "Gene",
                            "id": "SPRY4"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/246/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/246/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/246/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "442",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:09.219553"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI648"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/442/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/442/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        },
                        {
                            "type": "Gene",
                            "id": "PROKR2"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/442/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/442/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/442/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "443",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:09.263540"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI649"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/443/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/443/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "IGSF10"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/443/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/443/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/443/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "444",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:09.297685"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI650"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/444/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/444/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "HS6ST1"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/444/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/444/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/444/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "445",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Directly interacting",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:09.339645"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI651"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/445/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/445/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "CCDC141"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        },
                        {
                            "type": "Gene",
                            "id": "SEMA3E"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/445/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/445/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/445/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "446",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Same pathway",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [
                    "(NRP1, PLXNA1)"
                ],
                "common_pathways": [
                    "Semaphorin interactions",
                    "Nervous system development",
                    "Axon guidance",
                    "Sema3A PAK dependent Axon repulsion",
                    "Developmental Biology",
                    "SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"
                ],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:09.385525"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI652"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/446/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/446/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "FGFR1"
                        },
                        {
                            "type": "Gene",
                            "id": "NRP1"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/446/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/446/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/446/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "447",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:09.416299"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI653"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/447/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/447/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        },
                        {
                            "type": "Gene",
                            "id": "POLR3A"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/447/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/447/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/447/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "448",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Monogenic experiments only",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:09.445667"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI654"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/448/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/448/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        },
                        {
                            "type": "Gene",
                            "id": "SRA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/448/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/448/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/448/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "641",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:20.563510"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI874"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/641/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/641/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "DLX5"
                        },
                        {
                            "type": "Gene",
                            "id": "EGF"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/641/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/641/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/641/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "675",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:22.248720"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI912"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/675/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/675/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "CHD7"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/675/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/675/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/675/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "988",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2023-05-16T12:03:27.375090"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1411"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/988/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/988/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ANOS1"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        },
                        {
                            "type": "Gene",
                            "id": "PNPLA6"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/988/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/988/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/988/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "999",
            "attributes": {
                "gene_relationship": [
                    "Relevant pathways for phenotype",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2023-05-16T12:03:27.426106"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1423"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/999/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/999/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "FGFR1"
                        },
                        {
                            "type": "Gene",
                            "id": "PLXNA1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/999/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/999/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/999/?format=api"
            }
        }
    ]
}