Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/PAX6/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "645", "attributes": { "gene_relationship": [ "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "secretion", "Signaling pathways regulating pluripotency of stem cells", "Peptide hormone metabolism", "Synthesis", "Metabolism of proteins" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:20.813021" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI879" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/645/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/645/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "IGF1" }, { "type": "Gene", "id": "PAX6" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/645/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/645/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/645/?format=api" } }, { "type": "GeneCombination", "id": "646", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:20.882062" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI880" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/646/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/646/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "FEZ1" }, { "type": "Gene", "id": "IGF1" }, { "type": "Gene", "id": "PAX6" }, { "type": "Gene", "id": "PLXNB1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/646/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/646/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/646/?format=api" } }, { "type": "GeneCombination", "id": "651", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Signal Transduction" ], "genecomb_metascore": 0, "lastmodified": "2021-10-18T11:01:21.149087" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI885" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/651/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/651/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ANOS1" }, { "type": "Gene", "id": "PAX6" }, { "type": "Gene", "id": "PLXNB1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/651/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/651/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/651/?format=api" } }, { "type": "GeneCombination", "id": "653", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "GPCR downstream signalling", "Class A/1 (Rhodopsin-like receptors)", "Signaling by GPCR", "Developmental Biology", "Peptide ligand-binding receptors", "Signal Transduction", "GPCR ligand binding" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:21.247449" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI887" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/653/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/653/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "EDNRB" }, { "type": "Gene", "id": "PAX6" }, { "type": "Gene", "id": "PROKR2" }, { "type": "Gene", "id": "RELN" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/653/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/653/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/653/?format=api" } } ] }