Gene Instance
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genes/NRP1/?format=api
{ "data": { "type": "Gene", "id": "NRP1", "attributes": { "go_molecular_function": [ "vascular endothelial growth factor-activated receptor activity", "protein binding", "metal ion binding" ], "pathway_id": [ "R-HSA-162582", "kegg_path:hsa05171", "R-HSA-399956", "kegg_path:hsa04360", "R-HSA-376176", "R-HSA-373755", "R-HSA-422475", "R-HSA-194138", "R-HSA-373760", "R-HSA-399954", "R-HSA-445144", "R-HSA-9675108", "R-HSA-447041", "kegg_path:hsa05166", "R-HSA-194306", "R-HSA-1266738", "R-HSA-9006934", "R-HSA-399955" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "O14786", "ensembl_id": "ENSG00000099250", "entrez_id": "8829", "chromosome_number": "10" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1306" }, { "type": "SmallVariant", "id": "1420" }, { "type": "SmallVariant", "id": "1877" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NRP1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NRP1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "410" }, { "type": "GeneCombination", "id": "446" }, { "type": "GeneCombination", "id": "624" }, { "type": "GeneCombination", "id": "676" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NRP1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NRP1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NRP1/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:44.297539", "status": "CU", "curator": null, "submitter": "cnachteg" } }