Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/NOD2/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "97", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Immune System", "Cytokine Signaling in Immune system", "Tuberculosis", "Signaling by Interleukins" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:49.595024" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI130" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/97/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/97/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "IL10RA" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/97/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/97/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/97/?format=api" } }, { "type": "GeneCombination", "id": "874", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Monogenic experiments only", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:26.608390" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1241" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/874/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/874/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NOD2" }, { "type": "Gene", "id": "NPC1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/874/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/874/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/874/?format=api" } }, { "type": "GeneCombination", "id": "1266", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(MEFV, NLRP3)" ], "common_pathways": [ "Immune System" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:26:55.439025" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1788" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1266/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1266/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NLRP3" }, { "type": "Gene", "id": "NOD2" }, { "type": "Gene", "id": "TNFRSF1A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1266/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1266/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1266/?format=api" } }, { "type": "GeneCombination", "id": "1265", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:27:09.438299" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1785" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1265/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1265/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "NLRP12" }, { "type": "Gene", "id": "NOD2" }, { "type": "Gene", "id": "TNFRSF1A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1265/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1265/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1265/?format=api" } }, { "type": "GeneCombination", "id": "1264", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NOD-like receptor signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:27:20.737362" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1781" }, { "type": "Combination", "id": "OLI1782" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1264/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1264/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NLRP12" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1264/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1264/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1264/?format=api" } }, { "type": "GeneCombination", "id": "1263", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NOD-like receptor signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:27:32.368440" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1778" }, { "type": "Combination", "id": "OLI1779" }, { "type": "Combination", "id": "OLI1780" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1263/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1263/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "NLRP12" }, { "type": "Gene", "id": "NLRP3" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1263/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1263/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1263/?format=api" } }, { "type": "GeneCombination", "id": "1262", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(MEFV, NLRP3)" ], "common_pathways": [ "NOD-like receptor signaling pathway", "Immune System", "Innate Immune System", "Nucleotide-binding domain", "leucine rich repeat containing receptor (NLR) signaling pathways" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:27:47.292401" }, "relationships": { "combination_set": { "meta": { "count": 4 }, "data": [ { "type": "Combination", "id": "OLI1777" }, { "type": "Combination", "id": "OLI1786" }, { "type": "Combination", "id": "OLI1787" }, { "type": "Combination", "id": "OLI1789" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1262/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1262/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NLRP3" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1262/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1262/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1262/?format=api" } }, { "type": "GeneCombination", "id": "1261", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Immune System" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:28:02.772404" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1776" }, { "type": "Combination", "id": "OLI1783" }, { "type": "Combination", "id": "OLI1784" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1261/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1261/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NOD2" }, { "type": "Gene", "id": "TNFRSF1A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1261/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1261/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1261/?format=api" } }, { "type": "GeneCombination", "id": "1259", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NOD-like receptor signaling pathway", "Immune System", "Post-translational protein modification", "Innate Immune System", "Nucleotide-binding domain", "Metabolism of proteins", "leucine rich repeat containing receptor (NLR) signaling pathways", "Deubiquitination" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:28:33.999577" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI1768" }, { "type": "Combination", "id": "OLI1769" }, { "type": "Combination", "id": "OLI1770" }, { "type": "Combination", "id": "OLI1771" }, { "type": "Combination", "id": "OLI1772" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1259/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1259/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NLRP3" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1259/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1259/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1259/?format=api" } }, { "type": "GeneCombination", "id": "1260", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Tuberculosis", "Signaling by Interleukins", "Immune System", "Cytokine Signaling in Immune system", "TNF signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:28:24.643802" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1773" }, { "type": "Combination", "id": "OLI1774" }, { "type": "Combination", "id": "OLI1775" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1260/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1260/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NOD2" }, { "type": "Gene", "id": "TNFRSF1A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1260/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1260/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1260/?format=api" } }, { "type": "GeneCombination", "id": "1258", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NOD-like receptor signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:28:46.264113" }, "relationships": { "combination_set": { "meta": { "count": 8 }, "data": [ { "type": "Combination", "id": "OLI1760" }, { "type": "Combination", "id": "OLI1761" }, { "type": "Combination", "id": "OLI1762" }, { "type": "Combination", "id": "OLI1763" }, { "type": "Combination", "id": "OLI1764" }, { "type": "Combination", "id": "OLI1765" }, { "type": "Combination", "id": "OLI1766" }, { "type": "Combination", "id": "OLI1767" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1258/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1258/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "NLRP12" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1258/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1258/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1258/?format=api" } }, { "type": "GeneCombination", "id": "1257", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NOD-like receptor signaling pathway", "Immune System", "Innate Immune System", "Nucleotide-binding domain", "leucine rich repeat containing receptor (NLR) signaling pathways" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:28:56.289086" }, "relationships": { "combination_set": { "meta": { "count": 10 }, "data": [ { "type": "Combination", "id": "OLI1750" }, { "type": "Combination", "id": "OLI1751" }, { "type": "Combination", "id": "OLI1752" }, { "type": "Combination", "id": "OLI1753" }, { "type": "Combination", "id": "OLI1754" }, { "type": "Combination", "id": "OLI1755" }, { "type": "Combination", "id": "OLI1756" }, { "type": "Combination", "id": "OLI1757" }, { "type": "Combination", "id": "OLI1758" }, { "type": "Combination", "id": "OLI1759" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1257/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1257/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1257/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1257/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1257/?format=api" } } ] }