Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/MTHFR/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "293",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:00.908393"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI434"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/293/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/293/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "MTHFR"
                        },
                        {
                            "type": "Gene",
                            "id": "SCN2A"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/293/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/293/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/293/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "495",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Metabolism of vitamins and cofactors",
                    "Metabolism of water-soluble vitamins and cofactors",
                    "Pathways in cancer",
                    "Metabolism"
                ],
                "genecomb_metascore": 1,
                "lastmodified": "2021-10-18T11:01:11.365844"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI706"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/495/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/495/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "FZD2"
                        },
                        {
                            "type": "Gene",
                            "id": "MTHFR"
                        },
                        {
                            "type": "Gene",
                            "id": "SLC2A1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/495/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/495/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/495/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "498",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Same pathway",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Carbon metabolism",
                    "Metabolic pathways",
                    "Metabolism"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2021-10-18T11:01:11.468455"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI709"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/498/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/498/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "GLDC"
                        },
                        {
                            "type": "Gene",
                            "id": "MTHFR"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/498/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/498/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/498/?format=api"
            }
        }
    ]
}