Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/EML6/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "1193",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:22.181544"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1680"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1193/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1193/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 5
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "CDH23"
                        },
                        {
                            "type": "Gene",
                            "id": "CDHR1"
                        },
                        {
                            "type": "Gene",
                            "id": "CPSF3"
                        },
                        {
                            "type": "Gene",
                            "id": "EML6"
                        },
                        {
                            "type": "Gene",
                            "id": "SLC4A4"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1193/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1193/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1193/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1202",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:22.382711"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1689"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1202/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1202/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "COL9A3"
                        },
                        {
                            "type": "Gene",
                            "id": "EML6"
                        },
                        {
                            "type": "Gene",
                            "id": "TTN"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1202/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1202/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1202/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1207",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [],
                "common_pathways": [],
                "genecomb_metascore": 1,
                "lastmodified": "2024-02-29T15:02:22.506674"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1694"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1207/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1207/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 4
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ADAMTS7"
                        },
                        {
                            "type": "Gene",
                            "id": "COL5A3"
                        },
                        {
                            "type": "Gene",
                            "id": "DOCK9"
                        },
                        {
                            "type": "Gene",
                            "id": "EML6"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1207/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1207/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1207/?format=api"
            }
        }
    ]
}