Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/COL17A1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "95", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Involved in the same disease", "Relevant pathways for phenotype", "Colocalization", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Cell junction organization", "Extracellular matrix organization", "Assembly of collagen fibrils and other multimeric structures", "Collagen formation", "Degradation of the extracellular matrix", "Cell-Cell communication", "Type I hemidesmosome assembly" ], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:00:49.445622" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI126" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/95/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/95/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL17A1" }, { "type": "Gene", "id": "LAMB3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/95/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/95/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/95/?format=api" } }, { "type": "GeneCombination", "id": "301", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:01.194740" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI443" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/301/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/301/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL17A1" }, { "type": "Gene", "id": "EXPH5" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/301/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/301/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/301/?format=api" } }, { "type": "GeneCombination", "id": "389", "attributes": { "gene_relationship": [ "Affecting the same tissue", "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cell junction organization", "Extracellular matrix organization", "Assembly of collagen fibrils and other multimeric structures", "Collagen formation", "Degradation of the extracellular matrix", "Cell-Cell communication", "Type I hemidesmosome assembly", "Signal Transduction" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:05.919713" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI577" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/389/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/389/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "COL17A1" }, { "type": "Gene", "id": "DKK1" }, { "type": "Gene", "id": "LAMA3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/389/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/389/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/389/?format=api" } }, { "type": "GeneCombination", "id": "1161", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:34:55.629045" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1642" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1161/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1161/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL17A1" }, { "type": "Gene", "id": "RELT" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1161/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1161/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1161/?format=api" } }, { "type": "GeneCombination", "id": "1240", "attributes": { "gene_relationship": [ "Involved in the same disease", "Relevant pathways for phenotype", "Affecting the same tissue" ], "protein_interactions": [], "common_pathways": [ "Assembly of collagen fibrils and other multimeric structures", "Cell-Cell communication", "Degradation of the extracellular matrix", "Collagen formation", "Cell junction organization", "Type I hemidesmosome assembly", "Extracellular matrix organization" ], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:32:09.357251" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1733" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1240/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1240/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "COL17A1" }, { "type": "Gene", "id": "LAMA3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1240/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1240/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1240/?format=api" } } ] }