Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/BBS1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "32", "attributes": { "gene_relationship": [ "Affecting the same tissue", "Colocalization", "Directly interacting", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS1, CCDC28B)" ], "common_pathways": [], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:00:46.397124" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI037" }, { "type": "Combination", "id": "OLI038" }, { "type": "Combination", "id": "OLI039" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/32/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/32/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "CCDC28B" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/32/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/32/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/32/?format=api" } }, { "type": "GeneCombination", "id": "44", "attributes": { "gene_relationship": [ "Directly interacting", "Involved in the same disease", "Affecting the same tissue", "Same pathway", "Monogenic experiments only" ], "protein_interactions": [ "(BBS1, BBS4)" ], "common_pathways": [ "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.164245" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI062" }, { "type": "Combination", "id": "OLI1116" }, { "type": "Combination", "id": "OLI1117" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/44/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/44/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/44/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/44/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/44/?format=api" } }, { "type": "GeneCombination", "id": "46", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype", "Same pathway", "Monogenic experiments only" ], "protein_interactions": [ "(BBS1, BBS2)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.239871" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI064" }, { "type": "Combination", "id": "OLI065" }, { "type": "Combination", "id": "OLI139" }, { "type": "Combination", "id": "OLI417" }, { "type": "Combination", "id": "OLI1122" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/46/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/46/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/46/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/46/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/46/?format=api" } }, { "type": "GeneCombination", "id": "57", "attributes": { "gene_relationship": [ "Involved in the same disease", "Similar function", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.779901" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI079" }, { "type": "Combination", "id": "OLI1127" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/57/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "BBS12" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/57/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/57/?format=api" } }, { "type": "GeneCombination", "id": "58", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:47.823830" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI147" }, { "type": "Combination", "id": "OLI080" }, { "type": "Combination", "id": "OLI323" }, { "type": "Combination", "id": "OLI1120" }, { "type": "Combination", "id": "OLI1129" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/58/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/58/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS12" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/58/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/58/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/58/?format=api" } }, { "type": "GeneCombination", "id": "64", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:48.135441" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI088" }, { "type": "Combination", "id": "OLI089" }, { "type": "Combination", "id": "OLI619" }, { "type": "Combination", "id": "OLI1118" }, { "type": "Combination", "id": "OLI1119" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/64/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/64/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS10" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/64/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/64/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/64/?format=api" } }, { "type": "GeneCombination", "id": "104", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(BBS1, TTC8)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:49.947289" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI140" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/104/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/104/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "TTC8" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/104/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/104/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/104/?format=api" } }, { "type": "GeneCombination", "id": "105", "attributes": { "gene_relationship": [ "Directly interacting", "Same protein complex", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(BBS1, BBS9)" ], "common_pathways": [ "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:49.977652" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI141" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/105/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/105/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS9" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/105/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/105/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/105/?format=api" } }, { "type": "GeneCombination", "id": "213", "attributes": { "gene_relationship": [ "Involved in the same disease", "Indirectly interacting", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS1, CEP290)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:55.553158" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI324" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/213/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/213/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS10" }, { "type": "Gene", "id": "CEP290" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/213/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/213/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/213/?format=api" } }, { "type": "GeneCombination", "id": "423", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS1, BBS4)", "(BBS1, BBS5)", "(BBS1, BBS7)", "(BBS4, BBS5)", "(BBS4, BBS7)", "(BBS5, BBS7)" ], "common_pathways": [ "Cilium Assembly", "Organelle biogenesis and maintenance", "Cargo trafficking to the periciliary membrane", "BBSome-mediated cargo-targeting to cilium", "Cargo trafficking to the periciliary membrane" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:08.160738" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI617" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/423/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/423/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "BBS4" }, { "type": "Gene", "id": "BBS5" }, { "type": "Gene", "id": "BBS7" }, { "type": "Gene", "id": "NPHP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/423/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/423/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/423/?format=api" } }, { "type": "GeneCombination", "id": "1010", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 0, "lastmodified": "2023-05-16T12:03:27.499847" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1439" }, { "type": "Combination", "id": "OLI1440" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1010/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1010/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "IFT172" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1010/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1010/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1010/?format=api" } }, { "type": "GeneCombination", "id": "1011", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.508326" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1442" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1011/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1011/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ALMS1" }, { "type": "Gene", "id": "BBS1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1011/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1011/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1011/?format=api" } }, { "type": "GeneCombination", "id": "45", "attributes": { "gene_relationship": [ "Colocalization", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "BBSome-mediated cargo-targeting to cilium", "Cilium Assembly", "Organelle biogenesis and maintenance", "Cargo trafficking to the periciliary membrane" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:32:39.692747" }, "relationships": { "combination_set": { "meta": { "count": 5 }, "data": [ { "type": "Combination", "id": "OLI063" }, { "type": "Combination", "id": "OLI066" }, { "type": "Combination", "id": "OLI1436" }, { "type": "Combination", "id": "OLI1437" }, { "type": "Combination", "id": "OLI1435" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/45/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/45/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "MKKS" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/45/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/45/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/45/?format=api" } }, { "type": "GeneCombination", "id": "1014", "attributes": { "gene_relationship": [ "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 2, "lastmodified": "2023-05-16T12:03:27.521282" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1445" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1014/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1014/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "NPHP4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1014/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1014/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1014/?format=api" } }, { "type": "GeneCombination", "id": "1013", "attributes": { "gene_relationship": [ "Colocalization", "Indirectly interacting", "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 1, "lastmodified": "2024-03-01T14:21:44.003038" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1444" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1013/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1013/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "PDE6B" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1013/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1013/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1013/?format=api" } }, { "type": "GeneCombination", "id": "1180", "attributes": { "gene_relationship": [], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2024-02-29T15:02:21.890223" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1667" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1180/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1180/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "IFT172" }, { "type": "Gene", "id": "TRIM32" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1180/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1180/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1180/?format=api" } }, { "type": "GeneCombination", "id": "1012", "attributes": { "gene_relationship": [ "Colocalization", "Same pathway", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:21:54.586828" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1443" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1012/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1012/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "BBS1" }, { "type": "Gene", "id": "MKS1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1012/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1012/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1012/?format=api" } }, { "type": "GeneCombination", "id": "424", "attributes": { "gene_relationship": [ "Colocalization", "Same pathway", "Involved in the same disease" ], "protein_interactions": [ "(BBS1, BBS5)" ], "common_pathways": [ "BBSome-mediated cargo-targeting to cilium", "Cilium Assembly", "Organelle 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