Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/ALS2/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "558",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Pathways of neurodegeneration - multiple diseases"
                ],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:16.286389"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI772"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/558/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/558/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ALS2"
                        },
                        {
                            "type": "Gene",
                            "id": "C9orf72"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/558/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/558/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/558/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "562",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Amyotrophic lateral sclerosis",
                    "Pathways of neurodegeneration - multiple diseases"
                ],
                "genecomb_metascore": 0,
                "lastmodified": "2021-10-18T11:01:16.425204"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI778"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/562/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/562/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ALS2"
                        },
                        {
                            "type": "Gene",
                            "id": "SOD1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/562/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/562/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/562/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "712",
            "attributes": {
                "gene_relationship": [
                    "Same pathway",
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Pathways of neurodegeneration - multiple diseases",
                    "Amyotrophic lateral sclerosis"
                ],
                "genecomb_metascore": 0,
                "lastmodified": "2022-08-04T14:15:01.197435"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI955"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/712/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/712/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ALS2"
                        },
                        {
                            "type": "Gene",
                            "id": "ATXN2"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/712/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/712/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/712/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "1214",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease"
                ],
                "protein_interactions": [],
                "common_pathways": [
                    "Pathways of neurodegeneration - multiple diseases",
                    "Amyotrophic lateral sclerosis"
                ],
                "genecomb_metascore": 2,
                "lastmodified": "2024-02-29T15:02:22.676213"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI1704"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1214/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1214/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 3
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "ALS2"
                        },
                        {
                            "type": "Gene",
                            "id": "NEFH"
                        },
                        {
                            "type": "Gene",
                            "id": "SPG11"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/1214/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/1214/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/1214/?format=api"
            }
        }
    ]
}