Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/ALMS1/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "269", "attributes": { "gene_relationship": [ "Affecting the same tissue", "Same pathway", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:59.712053" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI402" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/269/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/269/combinations/?format=api" } }, "genes": { "meta": { "count": 5 }, "data": [ { "type": "Gene", "id": "ALMS1" }, { "type": "Gene", "id": "BMP4" }, { "type": "Gene", "id": "E2F4" }, { "type": "Gene", "id": "SMAD4" }, { "type": "Gene", "id": "TSHZ1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/269/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/269/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/269/?format=api" } }, { "type": "GeneCombination", "id": "421", "attributes": { "gene_relationship": [ "Involved in the same disease", "Affecting the same tissue", "Relevant pathways for phenotype" ], "protein_interactions": [ "(BBS4, BBS9)" ], "common_pathways": [ "Cilium Assembly", "Cargo trafficking to the periciliary membrane", "Organelle biogenesis and maintenance", "BBSome-mediated cargo-targeting to cilium" ], "genecomb_metascore": 3, "lastmodified": "2021-10-18T11:01:08.062866" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI615" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/421/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/421/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "ALMS1" }, { "type": "Gene", "id": "BBS4" }, { "type": "Gene", "id": "BBS9" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/421/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/421/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/421/?format=api" } }, { "type": "GeneCombination", "id": "1011", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype", "Involved in the same disease" ], "protein_interactions": [], "common_pathways": [ "Organelle biogenesis and maintenance", "Cilium Assembly" ], "genecomb_metascore": 1, "lastmodified": "2023-05-16T12:03:27.508326" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1442" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1011/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1011/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "ALMS1" }, { "type": "Gene", "id": "BBS1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1011/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1011/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1011/?format=api" } } ] }