Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/994/genes/?format=api
{ "data": [ { "type": "Gene", "id": "PNPLA6", "attributes": { "go_molecular_function": [ "['lysophospholipase activity', 'phosphatidyl phospholipase B activity']" ], "pathway_id": [ "kegg_path:hsa00564", "R-HSA-1430728", "R-HSA-1483255", "R-HSA-1483257", "R-HSA-556833", "R-HSA-6814848" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q8IY17", "ensembl_id": "None", "entrez_id": "ENSG00000032444", "chromosome_number": "19", "lastmodified": "2021-10-18T11:00:44.696531" }, "relationships": { "variant_set": { "meta": { "count": 8 }, "data": [ { "type": "SmallVariant", "id": "1794" }, { "type": "SmallVariant", "id": "1855" }, { "type": "SmallVariant", "id": "2773" }, { "type": "SmallVariant", "id": "2918" }, { "type": "SmallVariant", "id": "2939" }, { "type": "SmallVariant", "id": "2968" }, { "type": "SmallVariant", "id": "2972" }, { "type": "SmallVariant", "id": "2979" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PNPLA6/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PNPLA6/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "594" }, { "type": "GeneCombination", "id": "616" }, { "type": "GeneCombination", "id": "927" }, { "type": "GeneCombination", "id": "968" }, { "type": "GeneCombination", "id": "977" }, { "type": "GeneCombination", "id": "988" }, { "type": "GeneCombination", "id": "990" }, { "type": "GeneCombination", "id": "994" }, { "type": "GeneCombination", "id": "997" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PNPLA6/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PNPLA6/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PNPLA6/?format=api" } }, { "type": "Gene", "id": "SMCHD1", "attributes": { "go_molecular_function": [ "['ATP hydrolysis activity', 'ATP binding', 'DNA binding', 'protein binding', 'protein homodimerization activity']" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "A6NHR9", "ensembl_id": "None", "entrez_id": "ENSG00000101596", "chromosome_number": "18", "lastmodified": "2021-10-18T11:00:44.630267" }, "relationships": { "variant_set": { "meta": { "count": 6 }, "data": [ { "type": "SmallVariant", "id": "100" }, { "type": "SmallVariant", "id": "2904" }, { "type": "SmallVariant", "id": "2928" }, { "type": "SmallVariant", "id": "2958" }, { "type": "SmallVariant", "id": "2970" }, { "type": "SmallVariant", "id": "2980" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SMCHD1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SMCHD1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "35" }, { "type": "GeneCombination", "id": "962" }, { "type": "GeneCombination", "id": "972" }, { "type": "GeneCombination", "id": "984" }, { "type": "GeneCombination", "id": "989" }, { "type": "GeneCombination", "id": "994" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SMCHD1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SMCHD1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SMCHD1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }