Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/915/genes/?format=api
{ "data": [ { "type": "Gene", "id": "AGRN", "attributes": { "go_molecular_function": [ "['structural constituent of cytoskeleton', 'dystroglycan binding', 'extracellular matrix structural constituent', 'calcium ion binding', 'protein binding', 'sialic acid binding', 'heparan sulfate proteoglycan binding', 'laminin binding', 'chondroitin sulfate binding']" ], "pathway_id": [ "kegg_path:hsa04512", "R-HSA-1266738", "R-HSA-1430728", "R-HSA-1474244", "R-HSA-162582", "R-HSA-1630316", "R-HSA-1638091", "R-HSA-1643685", "R-HSA-1793185", "R-HSA-196854", "R-HSA-1971475", "R-HSA-2022928", "R-HSA-2024096", "R-HSA-216083", "R-HSA-2187338", "R-HSA-3000171", "R-HSA-3000178", "R-HSA-3560782", "R-HSA-3560783", "R-HSA-3560801", "R-HSA-3656237", "R-HSA-3656253", "R-HSA-372790", "R-HSA-375165", "R-HSA-3781865", "R-HSA-388396", "R-HSA-418594", "R-HSA-419037", "R-HSA-422475", "R-HSA-4420332", "R-HSA-5668914", "R-HSA-6806667", "R-HSA-71387", "R-HSA-9675108", "R-HSA-975634" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O00468", "ensembl_id": "None", "entrez_id": "ENSG00000188157", "chromosome_number": "1", "lastmodified": "2022-08-04T14:14:58.602767" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2327" }, { "type": "SmallVariant", "id": "2749" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AGRN/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AGRN/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "783" }, { "type": "GeneCombination", "id": "915" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/AGRN/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/AGRN/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/AGRN/?format=api" } }, { "type": "Gene", "id": "RPL3L", "attributes": { "go_molecular_function": [ "['structural constituent of ribosome', 'RNA binding']" ], "pathway_id": [ "kegg_path:hsa03010", "kegg_path:hsa05171", "R-HSA-1266738", "R-HSA-1430728", "R-HSA-156827", "R-HSA-156842", "R-HSA-156902", "R-HSA-1643685", "R-HSA-168255", "R-HSA-168273", "R-HSA-1799339", "R-HSA-192823", "R-HSA-2262752", "R-HSA-2408522", "R-HSA-2408557", "R-HSA-376176", "R-HSA-392499", "R-HSA-422475", "R-HSA-5663205", "R-HSA-6791226", "R-HSA-71291", "R-HSA-72312", "R-HSA-72613", "R-HSA-72689", "R-HSA-72706", "R-HSA-72737", "R-HSA-72764", "R-HSA-72766", "R-HSA-8868773", "R-HSA-8953854", "R-HSA-8953897", "R-HSA-9010553", "R-HSA-927802", "R-HSA-9633012", "R-HSA-9675108", "R-HSA-975956", "R-HSA-975957" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q92901", "ensembl_id": "None", "entrez_id": "ENSG00000140986", "chromosome_number": "16", "lastmodified": "2023-05-16T12:02:32.716556" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2748" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RPL3L/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RPL3L/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "915" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RPL3L/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RPL3L/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/RPL3L/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }