Combination List
This API endpoint handles listing (/combinations) and retrieval (/combinations/{combination_pk}/) of oligogenic combinations from the database
GET /api/genecombinations/890/combinations/?format=api
{ "data": [ { "type": "Combination", "id": "OLI1267", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 0, "functional_variant_evidence_metascore": 0, "functional_final_manual": 0, "functional_final_metascore": 0, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615266", "OMIM614838", "OMIM614840", "OMIM614839", "OMIM613370", "OMIM614841", "OMIM614880", "OMIM147950", "OMIM615270", "OMIM616329", "OMIM244200", "OMIM614837", "OMIM612225", "OMIM600496", "OMIM125851", "OMIM610628", "OMIM308700", "OMIM609812", "OMIM146110", "OMIM613375", "OMIM125850", "OMIM615269", "OMIM610508", "OMIM612702", "OMIM606391", "OMIM612370", "OMIM614842", "OMIM616511", "OMIM614858", "OMIM606392", "OMIM606394" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2023-05-16T12:02:43.648926" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "432" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1267/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1267/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2672" }, { "type": "SmallVariant", "id": "2673" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1267/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1267/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "937" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1267/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1267/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1267/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1267/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "890" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1267/?format=api" } }, { "type": "Combination", "id": "OLI1302", "attributes": { "scores": { "familial_evidence": 0, "statistical_evidence_manual": 1, "statistical_evidence_knowledge": 0, "statistical_evidence_metascore": 0, "functional_gene_evidence_manual": 1, "functional_gene_evidence_manual_harmonized": 1, "functional_gene_evidence_knowledge": 0, "functional_gene_evidence_metascore": 1, "functional_variant_evidence_manual": 0, "functional_variant_evidence_knowledge": 1, "functional_variant_evidence_metascore": 1, "functional_final_manual": 0, "functional_final_metascore": 1, "final_manual": 0, "final_metascore": 0 }, "omim_id": [ "OMIM615266", "OMIM614838", "OMIM616030", "OMIM614840", "OMIM615271", "OMIM614880", "OMIM147950", "OMIM615270", "OMIM244200", "OMIM614837", "OMIM610628", "OMIM308700", "OMIM615267", "OMIM618841", "OMIM614897", "OMIM615269", "OMIM612702", "OMIM612370", "OMIM614858" ], "oligogenic_effect": "Unknown", "status": "CU", "effect_predicted": false, "ethnicity": "Unknown", "lastmodified": "2023-05-16T12:02:45.898502" }, "relationships": { "diseases": { "meta": { "count": 1 }, "data": [ { "type": "Disease", "id": "478" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1302/relationships/diseases?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1302/diseases/?format=api" } }, "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2732" }, { "type": "SmallVariant", "id": "2733" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1302/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1302/variants/?format=api" } }, "reference_set": { "meta": { "count": 1 }, "data": [ { "type": "Reference", "id": "937" } ], "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1302/relationships/reference_set?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1302/references/?format=api" } }, "gene_combination": { "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1302/relationships/gene_combination?format=api", "related": "https://olida.ibsquare.be/api/combinations/OLI1302/genecombinations/?format=api" }, "data": { "type": "GeneCombination", "id": "890" } } }, "links": { "self": "https://olida.ibsquare.be/api/combinations/OLI1302/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }