Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/880/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ENPP1", "attributes": { "go_molecular_function": [ "['zinc ion binding', 'cyclic-GMP-AMP hydrolase activity', 'exonuclease activity', 'nucleotide diphosphatase activity', 'scavenger receptor activity', 'nucleic acid binding', 'calcium ion binding', 'ATP binding', 'NADH pyrophosphatase activity', 'phosphodiesterase I activity', 'dTTP diphosphatase activity', 'protein binding', \"3'-phosphoadenosine 5'-phosphosulfate binding\", 'protein homodimerization activity', 'insulin receptor binding', 'polysaccharide binding', 'nucleoside-triphosphate diphosphatase activity']" ], "pathway_id": [ "kegg_path:hsa00230", "kegg_path:hsa00240", "kegg_path:hsa00500", "kegg_path:hsa00740", "kegg_path:hsa00760", "kegg_path:hsa00770", "kegg_path:hsa01100", "R-HSA-1430728", "R-HSA-196843", "R-HSA-196849", "R-HSA-196854", "R-HSA-199220" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "None", "ensembl_id": "None", "entrez_id": "ENSG00000197594", "chromosome_number": "6", "lastmodified": "2023-05-16T12:02:32.519086" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2643" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ENPP1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ENPP1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "880" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ENPP1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ENPP1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ENPP1/?format=api" } }, { "type": "Gene", "id": "EXPH5", "attributes": { "go_molecular_function": [ "['small GTPase binding']" ], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "Q8NEV8", "ensembl_id": "None", "entrez_id": "ENSG00000110723", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.633036" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "943" }, { "type": "SmallVariant", "id": "2642" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EXPH5/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EXPH5/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "301" }, { "type": "GeneCombination", "id": "880" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/EXPH5/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/EXPH5/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/EXPH5/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }