Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/873/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "873",
        "attributes": {
            "gene_relationship": [
                "Relevant pathways for phenotype",
                "Same protein complex",
                "Co-expression",
                "Same pathway"
            ],
            "protein_interactions": [
                "(MCM2, MCM4)"
            ],
            "common_pathways": [
                "Cell Cycle",
                "Cell cycle",
                "Mitotic",
                "Synthesis of DNA",
                "Activation of ATR in response to replication stress",
                "DNA replication",
                "Unwinding of DNA",
                "Orc1 removal from chromatin",
                "Activation of the pre-replicative complex",
                "Mitotic G1 phase and G1/S transition",
                "Cell Cycle Checkpoints",
                "DNA Replication Pre-Initiation",
                "G2/M Checkpoints",
                "S Phase",
                "Assembly of the pre-replicative complex",
                "G1/S Transition",
                "DNA Replication",
                "Switching of origins to a post-replicative state",
                "DNA strand elongation"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2024-03-01T14:27:38.866112"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI1240"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/873/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/873/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "MCM2"
                    },
                    {
                        "type": "Gene",
                        "id": "MCM4"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/873/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/873/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/873/?format=api"
        }
    }
}