Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/868/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CXCL8", "attributes": { "go_molecular_function": [ "['interleukin-8 receptor binding', 'chemokine activity', 'CXCR chemokine receptor binding', 'protein binding', 'heparin binding']" ], "pathway_id": [ "kegg_path:hsa04060", "kegg_path:hsa04061", "kegg_path:hsa04062", "kegg_path:hsa04064", "kegg_path:hsa04072", "kegg_path:hsa04218", "kegg_path:hsa04620", "kegg_path:hsa04621", "kegg_path:hsa04622", "kegg_path:hsa04657", "kegg_path:hsa04932", "kegg_path:hsa04933", "kegg_path:hsa05120", "kegg_path:hsa05130", "kegg_path:hsa05131", "kegg_path:hsa05132", "kegg_path:hsa05133", "kegg_path:hsa05134", "kegg_path:hsa05135", "kegg_path:hsa05142", "kegg_path:hsa05144", "kegg_path:hsa05146", "kegg_path:hsa05161", "kegg_path:hsa05163", "kegg_path:hsa05164", "kegg_path:hsa05167", "kegg_path:hsa05171", "kegg_path:hsa05200", "kegg_path:hsa05202", "kegg_path:hsa05219", "kegg_path:hsa05323", "R-HSA-1280215", "R-HSA-162582", "R-HSA-168256", "R-HSA-2262752", "R-HSA-2559582", "R-HSA-2559583", "R-HSA-372790", "R-HSA-373076", "R-HSA-375276", "R-HSA-380108", "R-HSA-380994", "R-HSA-381042", "R-HSA-381119", "R-HSA-388396", "R-HSA-392499", "R-HSA-418594", "R-HSA-449147", "R-HSA-500792", "R-HSA-6783783", "R-HSA-6785807", "R-HSA-8953897" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P10145", "ensembl_id": "None", "entrez_id": "ENSG00000169429", "chromosome_number": "4", "lastmodified": "2023-05-16T12:02:32.399679" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2615" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CXCL8/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CXCL8/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "868" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CXCL8/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CXCL8/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CXCL8/?format=api" } }, { "type": "Gene", "id": "H6PD", "attributes": { "go_molecular_function": [ "['carbohydrate binding', 'NADP binding', 'glucose 1-dehydrogenase (NAD+) activity', '6-phosphogluconolactonase activity', 'glucose-6-phosphate dehydrogenase activity', 'glucose 1-dehydrogenase (NADP+) activity']" ], "pathway_id": [ "kegg_path:hsa00030", "kegg_path:hsa01100", "kegg_path:hsa01200" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O95479", "ensembl_id": "None", "entrez_id": "ENSG00000049239", "chromosome_number": "1", "lastmodified": "2023-05-16T12:02:32.395875" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2614" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/H6PD/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/H6PD/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "868" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/H6PD/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/H6PD/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/H6PD/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }