Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/843/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ACADS", "attributes": { "go_molecular_function": [ "acyl-CoA dehydrogenase activity", "flavin adenine dinucleotide binding", "butyryl-CoA dehydrogenase activity" ], "pathway_id": [ "kegg_path:hsa01200", "R-HSA-1430728", "kegg_path:hsa00650", "kegg_path:hsa00071", "kegg_path:hsa00640", "kegg_path:hsa01100", "kegg_path:hsa00410", "kegg_path:hsa01212", "R-HSA-77286", "kegg_path:hsa01100", "kegg_path:hsa00640", "kegg_path:hsa01212", "kegg_path:hsa00410", "kegg_path:hsa00071", "R-HSA-8978868", "kegg_path:hsa00650", "R-HSA-77350", "kegg_path:hsa01200", "kegg_path:hsa00280", "kegg_path:hsa00280", "R-HSA-77289", "R-HSA-77352", "R-HSA-556833" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P16219", "ensembl_id": "ENSG00000122971", "entrez_id": "35", "chromosome_number": "12", "lastmodified": "2022-08-04T14:14:59.817001" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2489" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ACADS/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ACADS/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "843" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ACADS/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ACADS/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ACADS/?format=api" } }, { "type": "Gene", "id": "ECHDC1", "attributes": { "go_molecular_function": [ "carboxy-lyase activity", "enoyl-CoA hydratase activity", "protein binding" ], "pathway_id": [ "kegg_path:hsa00640", "kegg_path:hsa01100" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9NTX5", "ensembl_id": "ENSG00000093144", "entrez_id": "55862", "chromosome_number": "6", "lastmodified": "2022-08-04T14:14:57.525962" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "2488" }, { "type": "SmallVariant", "id": "2490" }, { "type": "SmallVariant", "id": "2491" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ECHDC1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ECHDC1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "843" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ECHDC1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ECHDC1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ECHDC1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }