Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/841/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ITGB7", "attributes": { "go_molecular_function": [ "virus receptor activity", "protein binding", "cell adhesion molecule binding", "metal ion binding", "signaling receptor activity", "integrin binding" ], "pathway_id": [ "kegg_path:hsa04510", "kegg_path:hsa05414", "R-HSA-168256", "kegg_path:hsa04514", "kegg_path:hsa04151", "kegg_path:hsa04810", "kegg_path:hsa05202", "R-HSA-1280218", "R-HSA-216083", "R-HSA-1474244", "kegg_path:hsa04672", "kegg_path:hsa05165", "kegg_path:hsa05412", "R-HSA-198933", "kegg_path:hsa04512", "kegg_path:hsa05410" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P26010", "ensembl_id": "ENSG00000139626", "entrez_id": "3695", "chromosome_number": "12", "lastmodified": "2022-08-04T14:14:59.616808" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2485" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITGB7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITGB7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "841" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ITGB7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ITGB7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ITGB7/?format=api" } }, { "type": "Gene", "id": "PTPN13", "attributes": { "go_molecular_function": [ "protein tyrosine phosphatase activity", "protein binding", "phosphatidylinositol 3-kinase regulatory subunit binding" ], "pathway_id": [ "R-HSA-1483255", "R-HSA-556833", "R-HSA-1430728", "kegg_path:hsa04210", "R-HSA-9008059", "R-HSA-1280215", "R-HSA-168256", "R-HSA-446652", "R-HSA-1660499", "R-HSA-1483257", "R-HSA-449147" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q12923", "ensembl_id": "ENSG00000163629", "entrez_id": "5783", "chromosome_number": "4", "lastmodified": "2022-08-04T14:14:58.944656" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2484" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTPN13/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTPN13/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "841" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PTPN13/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PTPN13/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PTPN13/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }