Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/837/genes/?format=api
{ "data": [ { "type": "Gene", "id": "SPG7", "attributes": { "go_molecular_function": [ "protein binding", "ATP-dependent peptidase activity", "peptidase activity", "ATP hydrolysis activity", "unfolded protein binding", "ATP binding", "zinc ion binding", "metalloendopeptidase activity" ], "pathway_id": [ "R-HSA-382551", "R-HSA-8949215", "R-HSA-8949664" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "A0A2U3TZH1", "ensembl_id": "ENSG00000197912", "entrez_id": "6687", "chromosome_number": "16", "lastmodified": "2022-08-04T14:14:58.068653" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "2471" }, { "type": "SmallVariant", "id": "2474" }, { "type": "SmallVariant", "id": "2476" }, { "type": "SmallVariant", "id": "2479" }, { "type": "SmallVariant", "id": "2482" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SPG7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SPG7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "835" }, { "type": "GeneCombination", "id": "836" }, { "type": "GeneCombination", "id": "837" }, { "type": "GeneCombination", "id": "838" }, { "type": "GeneCombination", "id": "839" }, { "type": "GeneCombination", "id": "840" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SPG7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SPG7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SPG7/?format=api" } }, { "type": "Gene", "id": "TBCE", "attributes": { "go_molecular_function": [ "alpha-tubulin binding", "protein binding", "chaperone binding" ], "pathway_id": [ "R-HSA-391251", "R-HSA-389977", "R-HSA-392499" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q15813", "ensembl_id": "ENSG00000284770", "entrez_id": "6905", "chromosome_number": "1", "lastmodified": "2022-08-04T14:14:58.035446" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2477" }, { "type": "SmallVariant", "id": "2478" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TBCE/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TBCE/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "837" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TBCE/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TBCE/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TBCE/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }