Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/828/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CNOT1", "attributes": { "go_molecular_function": [ "protein domain specific binding", "protein binding", "retinoic acid receptor binding", "estrogen receptor binding", "armadillo repeat domain binding", "poly(A)-specific ribonuclease activity", "RNA binding", "molecular adaptor activity" ], "pathway_id": [ "R-HSA-212436", "R-HSA-3700989", "R-HSA-6791312", "R-HSA-6804115", "R-HSA-73857", "kegg_path:hsa03018", "R-HSA-429947", "R-HSA-74160", "R-HSA-8953854", "R-HSA-429914" ], "essential_gene": null, "status": "CU", "uniprot_acc": "A5YKK6", "ensembl_id": "ENSG00000125107", "entrez_id": "23019", "chromosome_number": "16", "lastmodified": "2022-08-04T14:14:58.861347" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2454" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNOT1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNOT1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "828" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNOT1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNOT1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CNOT1/?format=api" } }, { "type": "Gene", "id": "WNT4", "attributes": { "go_molecular_function": [ "['transcription corepressor activity', 'frizzled binding', 'receptor ligand activity', 'cytokine activity']" ], "pathway_id": [ "kegg_path:hsa04150", "kegg_path:hsa04310", "kegg_path:hsa04360", "kegg_path:hsa04390", "kegg_path:hsa04550", "kegg_path:hsa04916", "kegg_path:hsa04919", "kegg_path:hsa04934", "kegg_path:hsa05010", "kegg_path:hsa05022", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05205", "kegg_path:hsa05217", "kegg_path:hsa05224", "kegg_path:hsa05225", "kegg_path:hsa05226", "R-HSA-162582", "R-HSA-195721", "R-HSA-201681", "R-HSA-3238698", "R-HSA-372790", "R-HSA-373080", "R-HSA-3772470", "R-HSA-3858494", "R-HSA-4086400", "R-HSA-500792" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P56705", "ensembl_id": "None", "entrez_id": "ENSG00000162552", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.277654" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "1479" }, { "type": "SmallVariant", "id": "2455" }, { "type": "SmallVariant", "id": "2457" }, { "type": "SmallVariant", "id": "2607" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/WNT4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/WNT4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "472" }, { "type": "GeneCombination", "id": "828" }, { "type": "GeneCombination", "id": "829" }, { "type": "GeneCombination", "id": "864" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/WNT4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/WNT4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/WNT4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }