Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/788/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CCNB1IP1", "attributes": { "go_molecular_function": [ "metal ion binding", "identical protein binding", "ubiquitin protein ligase activity", "protein binding" ], "pathway_id": [], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9NPC3", "ensembl_id": "ENSG00000100814", "entrez_id": "57820", "chromosome_number": "14", "lastmodified": "2022-08-04T14:14:58.419108" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2336" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CCNB1IP1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CCNB1IP1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "788" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CCNB1IP1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CCNB1IP1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CCNB1IP1/?format=api" } }, { "type": "Gene", "id": "MLH3", "attributes": { "go_molecular_function": [ "protein binding", "ATP hydrolysis activity", "satellite DNA binding", "chromatin binding", "centromeric DNA binding", "ATP binding", "mismatched DNA binding" ], "pathway_id": [ "R-HSA-1500620", "R-HSA-1474165", "R-HSA-912446", "kegg_path:hsa03430", "R-HSA-1640170" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9UHC1", "ensembl_id": "ENSG00000119684", "entrez_id": "27030", "chromosome_number": "14", "lastmodified": "2022-08-04T14:14:59.094856" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2248" }, { "type": "SmallVariant", "id": "2337" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MLH3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MLH3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "759" }, { "type": "GeneCombination", "id": "788" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MLH3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MLH3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MLH3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }