Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/772/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ID1", "attributes": { "go_molecular_function": [ "proteasome binding", "protein binding", "transcription regulator inhibitor activity", "protein C-terminus binding", "identical protein binding", "protein N-terminus binding", "protein dimerization activity", "transcription regulator activity" ], "pathway_id": [ "kegg_path:hsa04390", "kegg_path:hsa04550", "R-HSA-9006934", "kegg_path:hsa04015", "R-HSA-9031628", "R-HSA-2262752", "R-HSA-8953897", "R-HSA-166520", "R-HSA-187037", "kegg_path:hsa04350", "R-HSA-162582", "R-HSA-198725", "R-HSA-2559583", "R-HSA-2559585" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P41134", "ensembl_id": "ENSG00000125968", "entrez_id": "3397", "chromosome_number": "20", "lastmodified": "2022-08-04T14:14:58.811404" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2303" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ID1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ID1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "772" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ID1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ID1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ID1/?format=api" } }, { "type": "Gene", "id": "TEX15", "attributes": { "go_molecular_function": [], "pathway_id": [ "R-HSA-1640170", "R-HSA-1474165", "R-HSA-912446", "R-HSA-1500620" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9BXT5", "ensembl_id": "ENSG00000133863", "entrez_id": "56154", "chromosome_number": "8", "lastmodified": "2022-08-04T14:14:58.152143" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2301" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TEX15/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TEX15/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "772" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TEX15/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TEX15/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TEX15/?format=api" } }, { "type": "Gene", "id": "TUBA8", "attributes": { "go_molecular_function": [ "structural constituent of cytoskeleton", "GTP binding", "protein binding", "GTPase activity" ], "pathway_id": [ "R-HSA-597592", "R-HSA-5617833", "R-HSA-195258", "R-HSA-2467813", "kegg_path:hsa05016", "kegg_path:hsa05014", "R-HSA-9675108", "R-HSA-422475", "R-HSA-112316", "R-HSA-1640170", "R-HSA-392499", "R-HSA-9609736", "R-HSA-8856688", "R-HSA-68877", "R-HSA-168256", "R-HSA-112314", "R-HSA-390466", "R-HSA-6811436", "kegg_path:hsa05010", "kegg_path:hsa05020", "R-HSA-948021", "R-HSA-2555396", "kegg_path:hsa04145", "kegg_path:hsa04210", "kegg_path:hsa05012", "R-HSA-6811442", "R-HSA-9648025", "R-HSA-157858", "R-HSA-2500257", "R-HSA-3371497", "R-HSA-391251", "R-HSA-2262752", "kegg_path:hsa05022", "R-HSA-1852241", "R-HSA-437239", "R-HSA-190828", "R-HSA-983231", "R-HSA-162582", "kegg_path:hsa04540", "R-HSA-983189", "R-HSA-389958", "R-HSA-8953897", "R-HSA-1266738", "R-HSA-9612973", "R-HSA-446203", "R-HSA-1632852", "R-HSA-69275", "kegg_path:hsa05132", "R-HSA-190861", "R-HSA-199991", "R-HSA-2132295", "R-HSA-5663205", "R-HSA-199977", "R-HSA-389960", "R-HSA-389977", "R-HSA-1643685", "R-HSA-1280218", "R-HSA-438064", "R-HSA-68882", "R-HSA-442755", "R-HSA-9646399", "R-HSA-190872", "R-HSA-6807878", "R-HSA-5663220", "R-HSA-9668328", "R-HSA-1445148", "R-HSA-373760", "R-HSA-5653656", "R-HSA-2995410", "R-HSA-109582", "R-HSA-112315", "R-HSA-453274", "R-HSA-9619483", "R-HSA-380320", "R-HSA-9609690", "R-HSA-9609646", "kegg_path:hsa05130", "R-HSA-9663891", "R-HSA-8955332", "R-HSA-194315", "R-HSA-6811434", "R-HSA-5626467", "R-HSA-68886", "kegg_path:hsa04530", "R-HSA-190840", "R-HSA-69278", "R-HSA-8852276" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9NY65", "ensembl_id": "ENSG00000183785", "entrez_id": "51807", "chromosome_number": "22", "lastmodified": "2022-08-04T14:14:59.044818" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2302" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TUBA8/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TUBA8/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "772" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TUBA8/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TUBA8/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TUBA8/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }