Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/756/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "756",
        "attributes": {
            "gene_relationship": [
                "Involved in the same disease",
                "Same protein complex",
                "Directly interacting",
                "Same pathway",
                "Relevant pathways for phenotype"
            ],
            "protein_interactions": [
                "(LAMA3, LAMB3)"
            ],
            "common_pathways": [
                "Extracellular matrix organization",
                "Toxoplasmosis",
                "Laminin interactions",
                "Pathways in cancer",
                "MET promotes cell motility",
                "Focal adhesion",
                "Signaling by MET",
                "Anchoring fibril formation",
                "Signal Transduction",
                "Amoebiasis",
                "Cell junction organization",
                "ECM-receptor interaction",
                "Non-integrin membrane-ECM interactions",
                "Cell-Cell communication",
                "PI3K-Akt signaling pathway",
                "Small cell lung cancer",
                "Signaling by Receptor Tyrosine Kinases",
                "Human papillomavirus infection",
                "MET activates PTK2 signaling",
                "Assembly of collagen fibrils and other multimeric structures",
                "Degradation of the extracellular matrix",
                "Type I hemidesmosome assembly",
                "Collagen formation"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2022-08-04T14:15:02.997772"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI1031"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/756/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/756/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "LAMA3"
                    },
                    {
                        "type": "Gene",
                        "id": "LAMB3"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/756/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/756/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/756/?format=api"
        }
    }
}