Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/755/genes/?format=api
{ "data": [ { "type": "Gene", "id": "POLG", "attributes": { "go_molecular_function": [ "protease binding", "protein binding", "DNA-directed DNA polymerase activity", "DNA binding", "chromatin binding", "3'-5' exonuclease activity" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P54098", "ensembl_id": "ENSG00000140521", "entrez_id": "5428", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.585795" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "235" }, { "type": "SmallVariant", "id": "272" }, { "type": "SmallVariant", "id": "1996" }, { "type": "SmallVariant", "id": "2229" }, { "type": "SmallVariant", "id": "2296" }, { "type": "SmallVariant", "id": "2297" }, { "type": "SmallVariant", "id": "2308" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/POLG/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/POLG/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "86" }, { "type": "GeneCombination", "id": "687" }, { "type": "GeneCombination", "id": "755" }, { "type": "GeneCombination", "id": "770" }, { "type": "GeneCombination", "id": "773" }, { "type": "GeneCombination", "id": "775" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/POLG/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/POLG/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/POLG/?format=api" } }, { "type": "Gene", "id": "PPFIA4", "attributes": { "go_molecular_function": [ "protein binding" ], "pathway_id": [ "R-HSA-212676", "R-HSA-112315", "R-HSA-112316", "R-HSA-181429", "R-HSA-210500", "R-HSA-6794362", "R-HSA-388844", "R-HSA-264642", "R-HSA-112310", "R-HSA-181430" ], "essential_gene": null, "status": "CU", "uniprot_acc": "O75335", "ensembl_id": "ENSG00000143847", "entrez_id": "8497", "chromosome_number": "1", "lastmodified": "2022-08-04T14:14:58.243984" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2228" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PPFIA4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PPFIA4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "755" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PPFIA4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PPFIA4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PPFIA4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }