Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/754/genes/?format=api
{ "data": [ { "type": "Gene", "id": "PDGFRB", "attributes": { "go_molecular_function": [ "platelet-derived growth factor-activated receptor activity", "platelet-derived growth factor receptor binding", "protein kinase binding", "platelet activating factor receptor activity", "protein binding", "enzyme binding", "phosphatidylinositol 3-kinase binding", "platelet-derived growth factor binding", "vascular endothelial growth factor binding", "signaling receptor binding", "protein serine/threonine/tyrosine kinase activity", "platelet-derived growth factor beta-receptor activity", "protein tyrosine kinase activity", "growth factor binding", "ATP binding", "transmembrane receptor protein tyrosine kinase activity" ], "pathway_id": [ "R-HSA-186763", "R-HSA-2219530", "kegg_path:hsa01521", "kegg_path:hsa04151", "kegg_path:hsa05206", "kegg_path:hsa05230", "R-HSA-1643685", "kegg_path:hsa04810", "kegg_path:hsa05231", "R-HSA-2219528", "kegg_path:hsa04015", "kegg_path:hsa04072", "R-HSA-199418", "kegg_path:hsa05218", "R-HSA-9006934", "kegg_path:hsa04020", "R-HSA-1257604", "R-HSA-162582", "R-HSA-9006925", "kegg_path:hsa04540", "kegg_path:hsa04010", "R-HSA-5684996", "kegg_path:hsa05200", "R-HSA-186797", "R-HSA-5663202", "R-HSA-5673001", "kegg_path:hsa04014", "R-HSA-5683057", "R-HSA-6811558", "kegg_path:hsa04630", "kegg_path:hsa05165", "kegg_path:hsa05215", "kegg_path:hsa05214", "kegg_path:hsa04510" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P09619", "ensembl_id": "ENSG00000113721", "entrez_id": "5159", "chromosome_number": "5", "lastmodified": "2022-08-04T14:14:59.708519" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2227" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PDGFRB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PDGFRB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "754" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PDGFRB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PDGFRB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PDGFRB/?format=api" } }, { "type": "Gene", "id": "SLC20A2", "attributes": { "go_molecular_function": [ "inorganic phosphate transmembrane transporter activity", "virus receptor activity", "sodium:phosphate symporter activity", "signaling receptor activity" ], "pathway_id": [ "R-HSA-425393", "R-HSA-427652", "R-HSA-1643685", "R-HSA-425407", "R-HSA-5619115", "R-HSA-5619111", "R-HSA-5619102", "R-HSA-382551" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q08357", "ensembl_id": "ENSG00000168575", "entrez_id": "6575", "chromosome_number": "8", "lastmodified": "2022-08-04T14:14:57.651272" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2226" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SLC20A2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SLC20A2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "754" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SLC20A2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SLC20A2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SLC20A2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }