Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/753/genes/?format=api
{ "data": [ { "type": "Gene", "id": "HSPG2", "attributes": { "go_molecular_function": [ "['extracellular matrix structural constituent conferring compression resistance', 'calcium ion binding', 'low-density lipoprotein particle receptor binding', 'protein C-terminus binding', 'protein binding', 'amyloid-beta binding']" ], "pathway_id": [ "kegg_path:hsa04512", "kegg_path:hsa05161", "kegg_path:hsa05205", "R-HSA-1430728", "R-HSA-1474228", "R-HSA-1474244", "R-HSA-162582", "R-HSA-1630316", "R-HSA-1638091", "R-HSA-1643685", "R-HSA-1793185", "R-HSA-196854", "R-HSA-1971475", "R-HSA-2022928", "R-HSA-2024096", "R-HSA-216083", "R-HSA-2187338", "R-HSA-3000157", "R-HSA-3000171", "R-HSA-3000178", "R-HSA-3560782", "R-HSA-3560783", "R-HSA-3560801", "R-HSA-3656237", "R-HSA-3656253", "R-HSA-372790", "R-HSA-3781865", "R-HSA-388396", "R-HSA-392499", "R-HSA-418594", "R-HSA-4420332", "R-HSA-5668914", "R-HSA-6806667", "R-HSA-71387", "R-HSA-975634", "R-HSA-977225" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P98160", "ensembl_id": "None", "entrez_id": "ENSG00000142798", "chromosome_number": "1", "lastmodified": "2022-08-04T14:14:58.093638" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "2224" }, { "type": "SmallVariant", "id": "2225" }, { "type": "SmallVariant", "id": "3527" }, { "type": "SmallVariant", "id": "3535" }, { "type": "SmallVariant", "id": "3553" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HSPG2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HSPG2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "753" }, { "type": "GeneCombination", "id": "1189" }, { "type": "GeneCombination", "id": "1192" }, { "type": "GeneCombination", "id": "1196" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/HSPG2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/HSPG2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/HSPG2/?format=api" } }, { "type": "Gene", "id": "PRMT7", "attributes": { "go_molecular_function": [ "protein binding", "histone-arginine N-methyltransferase activity", "[myelin basic protein]-arginine N-methyltransferase activity", "protein-arginine omega-N monomethyltransferase activity", "histone binding", "histone methyltransferase activity (H4-R3 specific)", "protein-arginine omega-N symmetric methyltransferase activity", "ribonucleoprotein complex binding", "S-adenosylmethionine-dependent methyltransferase activity" ], "pathway_id": [ "R-HSA-3214858", "R-HSA-3247509", "R-HSA-4839726" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q9NVM4", "ensembl_id": "ENSG00000132600", "entrez_id": "54496", "chromosome_number": "16", "lastmodified": "2022-08-04T14:14:59.011429" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2223" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PRMT7/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PRMT7/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "753" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PRMT7/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PRMT7/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PRMT7/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }