Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/751/genes/?format=api
{ "data": [ { "type": "Gene", "id": "BCKDHA", "attributes": { "go_molecular_function": [ "metal ion binding", "carboxy-lyase activity", "protein binding", "3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity" ], "pathway_id": [ "kegg_path:hsa00640", "kegg_path:hsa01100", "R-HSA-389661", "R-HSA-71291", "kegg_path:hsa00280", "R-HSA-1430728", "kegg_path:hsa00280", "R-HSA-70895", "kegg_path:hsa01100", "kegg_path:hsa00640" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P12694", "ensembl_id": "ENSG00000248098", "entrez_id": "593", "chromosome_number": "19", "lastmodified": "2022-08-04T14:14:58.794615" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2207" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BCKDHA/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BCKDHA/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "751" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/BCKDHA/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/BCKDHA/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/BCKDHA/?format=api" } }, { "type": "Gene", "id": "DBT", "attributes": { "go_molecular_function": [ "lipoic acid binding", "acetyltransferase activity", "ubiquitin protein ligase binding", "dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity" ], "pathway_id": [ "kegg_path:hsa00640", "R-HSA-70895", "R-HSA-71291", "kegg_path:hsa01100", "R-HSA-389661", "kegg_path:hsa00280", "R-HSA-1430728" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P11182", "ensembl_id": "ENSG00000137992", "entrez_id": "1629", "chromosome_number": "1", "lastmodified": "2022-08-04T14:15:00.067005" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2206" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DBT/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DBT/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "751" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DBT/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DBT/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DBT/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }