Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/733/genes/?format=api
{ "data": [ { "type": "Gene", "id": "LAMA2", "attributes": { "go_molecular_function": [ "['structural molecule activity', 'signaling receptor binding', 'extracellular matrix structural constituent']" ], "pathway_id": [ "kegg_path:hsa04151", "kegg_path:hsa04510", "kegg_path:hsa04512", "kegg_path:hsa05145", "kegg_path:hsa05146", "kegg_path:hsa05165", "kegg_path:hsa05200", "kegg_path:hsa05222", "kegg_path:hsa05410", "kegg_path:hsa05412", "kegg_path:hsa05414", "kegg_path:hsa05416", "R-HSA-1266738", "R-HSA-1474244", "R-HSA-162582", "R-HSA-3000157", "R-HSA-3000171", "R-HSA-3000178", "R-HSA-6806834", "R-HSA-8874081", "R-HSA-8875878", "R-HSA-9006934", "R-HSA-9619665", "R-HSA-9675108" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P24043", "ensembl_id": "None", "entrez_id": "ENSG00000196569", "chromosome_number": "6", "lastmodified": "2022-08-04T14:14:57.609595" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2128" }, { "type": "SmallVariant", "id": "3593" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LAMA2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LAMA2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "733" }, { "type": "GeneCombination", "id": "1210" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LAMA2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LAMA2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LAMA2/?format=api" } }, { "type": "Gene", "id": "LOXL4", "attributes": { "go_molecular_function": [ "protein-lysine 6-oxidase activity", "copper ion binding", "scavenger receptor activity", "protein binding" ], "pathway_id": [ "R-HSA-1566948", "R-HSA-2243919", "R-HSA-1474244", "R-HSA-1474290", "R-HSA-2022090" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q96JB6", "ensembl_id": "ENSG00000138131", "entrez_id": "84171", "chromosome_number": "10", "lastmodified": "2022-08-04T14:14:57.784839" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2129" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LOXL4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LOXL4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "733" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LOXL4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LOXL4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LOXL4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }