Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/704/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GRN", "attributes": { "go_molecular_function": [ "['growth factor activity', 'protein binding', 'RNA binding', 'cytokine activity', 'chaperone binding']" ], "pathway_id": [ "R-HSA-168249", "R-HSA-168256", "R-HSA-6798695" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P28799", "ensembl_id": "None", "entrez_id": "ENSG00000030582", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.551264" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1440" }, { "type": "SmallVariant", "id": "1815" }, { "type": "SmallVariant", "id": "2045" }, { "type": "SmallVariant", "id": "2087" }, { "type": "SmallVariant", "id": "3422" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GRN/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GRN/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "457" }, { "type": "GeneCombination", "id": "601" }, { "type": "GeneCombination", "id": "704" }, { "type": "GeneCombination", "id": "726" }, { "type": "GeneCombination", "id": "725" }, { "type": "GeneCombination", "id": "724" }, { "type": "GeneCombination", "id": "723" }, { "type": "GeneCombination", "id": "722" }, { "type": "GeneCombination", "id": "1148" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GRN/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GRN/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GRN/?format=api" } }, { "type": "Gene", "id": "TAF15", "attributes": { "go_molecular_function": [ "protein binding", "mRNA 3'-UTR binding", "DNA binding", "transcription coregulator activity", "metal ion binding", "RNA binding" ], "pathway_id": [ "R-HSA-162587", "R-HSA-167161", "kegg_path:hsa05202", "R-HSA-674695", "R-HSA-74160", "R-HSA-75953", "R-HSA-162906", "R-HSA-167172", "R-HSA-73857", "R-HSA-167162", "R-HSA-5633007", "R-HSA-73776", "R-HSA-212436", "R-HSA-3700989", "R-HSA-5663205", "R-HSA-162599", "R-HSA-73779", "kegg_path:hsa05202", "R-HSA-674695", "R-HSA-162587", "R-HSA-167161", "R-HSA-74160", "R-HSA-75953", "R-HSA-162906", "R-HSA-1643685", "kegg_path:hsa03022", "R-HSA-6804756", "R-HSA-76042", "R-HSA-167172", "R-HSA-73857", "R-HSA-167162", "R-HSA-5633007", "R-HSA-73776", "R-HSA-162599", "R-HSA-212436", "R-HSA-3700989", "R-HSA-5663205", "R-HSA-73779", "kegg_path:hsa03022", "R-HSA-1643685", "R-HSA-6804756", "R-HSA-76042" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q92804", "ensembl_id": "ENSG00000270647", "entrez_id": "8148", "chromosome_number": "17", "lastmodified": "2021-10-18T11:00:44.967410" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "545" }, { "type": "SmallVariant", "id": "2046" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TAF15/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TAF15/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "186" }, { "type": "GeneCombination", "id": "704" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TAF15/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TAF15/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TAF15/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }