Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/697/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ABCA13", "attributes": { "go_molecular_function": [ "ATPase-coupled transmembrane transporter activity", "lipid transporter activity", "ABC-type transporter activity", "ATP binding" ], "pathway_id": [ "kegg_path:hsa02010", "R-HSA-168249", "R-HSA-168256", "kegg_path:hsa02010", "R-HSA-6798695" ], "essential_gene": null, "status": "CU", "uniprot_acc": "A0A0A0MT16", "ensembl_id": "ENSG00000179869", "entrez_id": "154664", "chromosome_number": "7", "lastmodified": "2022-08-04T14:14:59.186514" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2024" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ABCA13/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ABCA13/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "697" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ABCA13/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ABCA13/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ABCA13/?format=api" } }, { "type": "Gene", "id": "SCN9A", "attributes": { "go_molecular_function": [ "voltage-gated ion channel activity", "voltage-gated sodium channel activity", "sodium ion binding" ], "pathway_id": [ "R-HSA-5576892", "R-HSA-1266738", "R-HSA-5576891", "kegg_path:hsa04742", "R-HSA-397014", "R-HSA-445095", "R-HSA-422475", "R-HSA-373760", "R-HSA-9675108" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q15858", "ensembl_id": "ENSG00000169432", "entrez_id": "6335", "chromosome_number": "2", "lastmodified": "2022-08-04T14:14:59.194818" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "2021" }, { "type": "SmallVariant", "id": "2023" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCN9A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCN9A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "696" }, { "type": "GeneCombination", "id": "697" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SCN9A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SCN9A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SCN9A/?format=api" } }, { "type": "Gene", "id": "SYT14", "attributes": { "go_molecular_function": [], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "None", "ensembl_id": "ENSG00000143469", "entrez_id": "255928", "chromosome_number": "1", "lastmodified": "2022-08-04T14:14:58.210407" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "2025" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SYT14/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SYT14/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "697" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SYT14/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SYT14/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SYT14/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2024 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }