Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/688/genes/?format=api
{ "data": [ { "type": "Gene", "id": "GALC", "attributes": { "go_molecular_function": [ "galactosylceramidase activity" ], "pathway_id": [ "kegg_path:hsa00600", "kegg_path:hsa04142", "R-HSA-1430728", "R-HSA-1660662", "R-HSA-428157", "kegg_path:hsa01100", "R-HSA-556833" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P54803", "ensembl_id": "ENSG00000054983", "entrez_id": "2581", "chromosome_number": "14", "lastmodified": "2021-10-18T11:00:44.752228" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "677" }, { "type": "SmallVariant", "id": "696" }, { "type": "SmallVariant", "id": "1999" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GALC/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GALC/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "220" }, { "type": "GeneCombination", "id": "223" }, { "type": "GeneCombination", "id": "688" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GALC/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GALC/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GALC/?format=api" } }, { "type": "Gene", "id": "GJA1", "attributes": { "go_molecular_function": [ "gap junction hemi-channel activity", "tubulin binding", "efflux transmembrane transporter activity", "scaffold protein binding", "protein binding", "ion transmembrane transporter activity", "gap junction channel activity involved in cell communication by electrical coupling", "signaling receptor binding", "gap junction channel activity", "beta-tubulin binding", "protein tyrosine kinase binding", "beta-catenin binding", "gap junction channel activity involved in cardiac conduction electrical coupling", "glutathione transmembrane transporter activity" ], "pathway_id": [ "R-HSA-190872", "kegg_path:hsa05412", "R-HSA-191650", "R-HSA-5653656", "R-HSA-157858", "R-HSA-190861", "R-HSA-199991", "R-HSA-196025", "R-HSA-190827", "R-HSA-190828", "R-HSA-190840", "R-HSA-190873", "R-HSA-190704", "kegg_path:hsa04540" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P17302", "ensembl_id": "ENSG00000152661", "entrez_id": "2697", "chromosome_number": "6", "lastmodified": "2022-08-04T14:14:58.352498" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1998" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GJA1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GJA1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "688" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/GJA1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/GJA1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/GJA1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }