Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/687/genes/?format=api
{ "data": [ { "type": "Gene", "id": "NAGA", "attributes": { "go_molecular_function": [ "protein homodimerization activity", "alpha-N-acetylgalactosaminidase activity", "alpha-galactosidase activity" ], "pathway_id": [ "kegg_path:hsa04142", "kegg_path:hsa04142", "kegg_path:hsa00603", "kegg_path:hsa00603", "kegg_path:hsa01100", "kegg_path:hsa01100" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P17050", "ensembl_id": "ENSG00000198951", "entrez_id": "4668", "chromosome_number": "22", "lastmodified": "2022-08-04T14:14:59.444959" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1997" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NAGA/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NAGA/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "687" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/NAGA/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/NAGA/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/NAGA/?format=api" } }, { "type": "Gene", "id": "POLG", "attributes": { "go_molecular_function": [ "protease binding", "protein binding", "DNA-directed DNA polymerase activity", "DNA binding", "chromatin binding", "3'-5' exonuclease activity" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P54098", "ensembl_id": "ENSG00000140521", "entrez_id": "5428", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.585795" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "235" }, { "type": "SmallVariant", "id": "272" }, { "type": "SmallVariant", "id": "1996" }, { "type": "SmallVariant", "id": "2229" }, { "type": "SmallVariant", "id": "2296" }, { "type": "SmallVariant", "id": "2297" }, { "type": "SmallVariant", "id": "2308" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/POLG/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/POLG/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "86" }, { "type": "GeneCombination", "id": "687" }, { "type": "GeneCombination", "id": "755" }, { "type": "GeneCombination", "id": "770" }, { "type": "GeneCombination", "id": "773" }, { "type": "GeneCombination", "id": "775" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/POLG/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/POLG/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/POLG/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }