Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/680/genes/?format=api
{ "data": [ { "type": "Gene", "id": "IL36RN", "attributes": { "go_molecular_function": [ "interleukin-1 receptor antagonist activity", "interleukin-1 receptor binding", "protein binding", "cytokine activity" ], "pathway_id": [ "kegg_path:hsa04060", "R-HSA-168256", "R-HSA-446652", "R-HSA-449147", "R-HSA-1280215", "R-HSA-9014826" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q9UBH0", "ensembl_id": "ENSG00000136695", "entrez_id": "26525", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.586734" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1454" }, { "type": "SmallVariant", "id": "1980" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IL36RN/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IL36RN/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "464" }, { "type": "GeneCombination", "id": "680" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/IL36RN/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/IL36RN/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/IL36RN/?format=api" } }, { "type": "Gene", "id": "SEC61A1", "attributes": { "go_molecular_function": [ "protein binding", "ribosome binding", "signal sequence binding", "calcium channel activity", "protein transmembrane transporter activity" ], "pathway_id": [ "kegg_path:hsa05110", "R-HSA-1280218", "R-HSA-392499", "kegg_path:hsa05110", "R-HSA-168256", "R-HSA-72766", "R-HSA-983169", "kegg_path:hsa04141", "R-HSA-1799339", "kegg_path:hsa03060", "kegg_path:hsa04145", "R-HSA-1236974", "kegg_path:hsa04141", "kegg_path:hsa04145", "kegg_path:hsa03060", "R-HSA-1236975" ], "essential_gene": null, "status": "CU", "uniprot_acc": "P61619", "ensembl_id": "ENSG00000058262", "entrez_id": "29927", "chromosome_number": "3", "lastmodified": "2022-08-04T14:14:57.759959" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1981" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEC61A1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEC61A1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "680" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEC61A1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEC61A1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SEC61A1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }