Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/679/genes/?format=api
{ "data": [ { "type": "Gene", "id": "C2orf74", "attributes": { "go_molecular_function": [], "pathway_id": [], "essential_gene": null, "status": "CU", "uniprot_acc": "A8MZ97", "ensembl_id": "ENSG00000237651", "entrez_id": "339804", "chromosome_number": "2", "lastmodified": "2022-08-04T14:14:57.509292" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1979" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C2orf74/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C2orf74/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "679" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/C2orf74/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/C2orf74/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/C2orf74/?format=api" } }, { "type": "Gene", "id": "MITF", "attributes": { "go_molecular_function": [ "protein binding", "DNA-binding transcription factor activity, RNA polymerase II-specific", "E-box binding", "DNA-binding transcription repressor activity, RNA polymerase II-specific", "DNA-binding transcription activator activity, RNA polymerase II-specific", "chromatin binding", "protein dimerization activity", "RNA polymerase II cis-regulatory region sequence-specific DNA binding" ], "pathway_id": [ "kegg_path:hsa05218", "R-HSA-2990846", "R-HSA-3108232", "R-HSA-3232118", "kegg_path:hsa04137", "kegg_path:hsa04380", "kegg_path:hsa04916", "kegg_path:hsa05202", "R-HSA-392499", "kegg_path:hsa05200", "R-HSA-597592" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O75030", "ensembl_id": "ENSG00000187098", "entrez_id": "4286", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.953700" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "489" }, { "type": "SmallVariant", "id": "860" }, { "type": "SmallVariant", "id": "1978" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MITF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MITF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "164" }, { "type": "GeneCombination", "id": "266" }, { "type": "GeneCombination", "id": "679" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MITF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MITF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MITF/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }