Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/677/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CNTN2", "attributes": { "go_molecular_function": [ "protein binding", "cell-cell adhesion mediator activity" ], "pathway_id": [ "R-HSA-373760", "R-HSA-375165", "R-HSA-9675108", "R-HSA-422475", "R-HSA-1266738", "R-HSA-447038", "R-HSA-419037", "kegg_path:hsa04514", "kegg_path:hsa04514" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q02246", "ensembl_id": "ENSG00000184144", "entrez_id": "6900", "chromosome_number": "1", "lastmodified": "2021-10-18T11:00:44.506076" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1862" }, { "type": "SmallVariant", "id": "1971" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNTN2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNTN2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "619" }, { "type": "GeneCombination", "id": "677" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CNTN2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CNTN2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CNTN2/?format=api" } }, { "type": "Gene", "id": "LHB", "attributes": { "go_molecular_function": [ "signaling receptor binding", "protein binding", "hormone activity" ], "pathway_id": [ "R-HSA-1643685", "R-HSA-209822", "R-HSA-948021", "kegg_path:hsa04917", "R-HSA-1430728", "R-HSA-196071", "kegg_path:hsa04080", "kegg_path:hsa04912", "kegg_path:hsa04929", "R-HSA-9658195", "R-HSA-597592", "R-HSA-9662851", "kegg_path:hsa04913", "kegg_path:hsa04024", "R-HSA-162582", "R-HSA-372790", "R-HSA-375281", "R-HSA-193048", "R-HSA-500792", "R-HSA-209952", "R-HSA-9664433", "R-HSA-975578", "kegg_path:hsa04917", "R-HSA-446203", "R-HSA-418555", "R-HSA-193993", "R-HSA-556833", "kegg_path:hsa04080", "R-HSA-373076", "R-HSA-9660821", "R-HSA-975576", "R-HSA-5663205", "kegg_path:hsa04912", "kegg_path:hsa04929", "R-HSA-388396", "kegg_path:hsa04024", "kegg_path:hsa04913", "R-HSA-2980736", "R-HSA-392499", "R-HSA-8957322" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P01229", "ensembl_id": "ENSG00000104826", "entrez_id": "3972", "chromosome_number": "19", "lastmodified": "2021-10-18T11:00:44.394017" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "1880" }, { "type": "SmallVariant", "id": "1939" }, { "type": "SmallVariant", "id": "1941" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LHB/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LHB/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 8 }, "data": [ { "type": "GeneCombination", "id": "625" }, { "type": "GeneCombination", "id": "656" }, { "type": "GeneCombination", "id": "657" }, { "type": "GeneCombination", "id": "658" }, { "type": "GeneCombination", "id": "672" }, { "type": "GeneCombination", "id": "674" }, { "type": "GeneCombination", "id": "677" }, { "type": "GeneCombination", "id": "815" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LHB/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LHB/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LHB/?format=api" } }, { "type": "Gene", "id": "SEMA7A", "attributes": { "go_molecular_function": [ "['integrin binding', 'semaphorin receptor binding', 'protein binding', 'chemorepellent activity']" ], "pathway_id": [ "kegg_path:hsa04360", "R-HSA-1266738", "R-HSA-373755", "R-HSA-416700", "R-HSA-422475", "R-HSA-9675108" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O75326", "ensembl_id": "None", "entrez_id": "ENSG00000138623", "chromosome_number": "15", "lastmodified": "2021-10-18T11:00:44.948272" }, "relationships": { "variant_set": { "meta": { "count": 10 }, "data": [ { "type": "SmallVariant", "id": "775" }, { "type": "SmallVariant", "id": "1895" }, { "type": "SmallVariant", "id": "1940" }, { "type": "SmallVariant", "id": "1965" }, { "type": "SmallVariant", "id": "1972" }, { "type": "SmallVariant", "id": "2580" }, { "type": "SmallVariant", "id": "2673" }, { "type": "SmallVariant", "id": "2711" }, { "type": "SmallVariant", "id": "2733" }, { "type": "SmallVariant", "id": "2961" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA7A/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEMA7A/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "242" }, { "type": "GeneCombination", "id": "633" }, { "type": "GeneCombination", "id": "657" }, { "type": "GeneCombination", "id": "673" }, { "type": "GeneCombination", "id": "677" }, { "type": "GeneCombination", "id": "859" }, { "type": "GeneCombination", "id": "890" }, { "type": "GeneCombination", "id": "901" }, { "type": "GeneCombination", "id": "985" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA7A/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/SEMA7A/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/SEMA7A/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 3 } }