Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/667/genes/?format=api
{ "data": [ { "type": "Gene", "id": "B4GAT1", "attributes": { "go_molecular_function": [ "glycosyltransferase activity", "transferase activity", "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity", "glucuronosyltransferase activity", "metal ion binding" ], "pathway_id": [ "R-HSA-1643685", "kegg_path:hsa00515", "R-HSA-3781865", "R-HSA-597592", "R-HSA-5173105", "R-HSA-392499", "R-HSA-2022854", "R-HSA-5668914", "R-HSA-1638074", "R-HSA-5083627", "R-HSA-1630316", "R-HSA-3906995", "R-HSA-71387", "R-HSA-1430728", "kegg_path:hsa01100" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O43505", "ensembl_id": "ENSG00000174684", "entrez_id": "11041", "chromosome_number": "11", "lastmodified": "2021-10-18T11:00:44.975874" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1885" }, { "type": "SmallVariant", "id": "1964" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/B4GAT1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/B4GAT1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 4 }, "data": [ { "type": "GeneCombination", "id": "628" }, { "type": "GeneCombination", "id": "667" }, { "type": "GeneCombination", "id": "671" }, { "type": "GeneCombination", "id": "672" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/B4GAT1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/B4GAT1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/B4GAT1/?format=api" } }, { "type": "Gene", "id": "DCC", "attributes": { "go_molecular_function": [ "['transmembrane signaling receptor activity', 'protein binding', 'netrin receptor activity']" ], "pathway_id": [ "kegg_path:hsa04360", "kegg_path:hsa05200", "kegg_path:hsa05210", "R-HSA-109581", "R-HSA-1266738", "R-HSA-373752", "R-HSA-376172", "R-HSA-376176", "R-HSA-418885", "R-HSA-418886", "R-HSA-418889", "R-HSA-418890", "R-HSA-422475", "R-HSA-428542", "R-HSA-5357769", "R-HSA-5357801", "R-HSA-9675108", "kegg_path:hsa04360", "kegg_path:hsa05200", "kegg_path:hsa05210" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P43146", "ensembl_id": "None", "entrez_id": "ENSG00000187323", "chromosome_number": "18", "lastmodified": "2021-10-18T11:00:44.731182" }, "relationships": { "variant_set": { "meta": { "count": 7 }, "data": [ { "type": "SmallVariant", "id": "1847" }, { "type": "SmallVariant", "id": "1872" }, { "type": "SmallVariant", "id": "1907" }, { "type": "SmallVariant", "id": "1955" }, { "type": "SmallVariant", "id": "2884" }, { "type": "SmallVariant", "id": "2949" }, { "type": "SmallVariant", "id": "2989" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DCC/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DCC/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 7 }, "data": [ { "type": "GeneCombination", "id": "613" }, { "type": "GeneCombination", "id": "622" }, { "type": "GeneCombination", "id": "640" }, { "type": "GeneCombination", "id": "667" }, { "type": "GeneCombination", "id": "954" }, { "type": "GeneCombination", "id": "981" }, { "type": "GeneCombination", "id": "998" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/DCC/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/DCC/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/DCC/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }