Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/655/genes/?format=api
{ "data": [ { "type": "Gene", "id": "LIF", "attributes": { "go_molecular_function": [ "leukemia inhibitory factor receptor binding", "cytokine activity", "growth factor activity" ], "pathway_id": [ "kegg_path:hsa04630", "kegg_path:hsa04550", "R-HSA-1280215", "R-HSA-6783589", "R-HSA-6788467", "kegg_path:hsa04668", "R-HSA-6783783", "R-HSA-449147", "R-HSA-6785807", "R-HSA-168256", "kegg_path:hsa04060" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P15018", "ensembl_id": "ENSG00000128342", "entrez_id": "3976", "chromosome_number": "22", "lastmodified": "2021-10-18T11:00:44.932159" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1938" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LIF/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LIF/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "655" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/LIF/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/LIF/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/LIF/?format=api" } }, { "type": "Gene", "id": "PLXNB1", "attributes": { "go_molecular_function": [ "semaphorin receptor activity", "GTPase activator activity", "protein binding" ], "pathway_id": [ "R-HSA-1266738", "R-HSA-416482", "R-HSA-9675108", "R-HSA-373755", "R-HSA-416572", "R-HSA-422475", "R-HSA-400685", "R-HSA-388396", "kegg_path:hsa04360", "R-HSA-416550", "R-HSA-162582", "R-HSA-372790" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "O43157", "ensembl_id": "ENSG00000164050", "entrez_id": "5364", "chromosome_number": "3", "lastmodified": "2021-10-18T11:00:44.887426" }, "relationships": { "variant_set": { "meta": { "count": 5 }, "data": [ { "type": "SmallVariant", "id": "1900" }, { "type": "SmallVariant", "id": "1915" }, { "type": "SmallVariant", "id": "1919" }, { "type": "SmallVariant", "id": "1935" }, { "type": "SmallVariant", "id": "1953" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PLXNB1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PLXNB1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 7 }, "data": [ { "type": "GeneCombination", "id": "644" }, { "type": "GeneCombination", "id": "636" }, { "type": "GeneCombination", "id": "646" }, { "type": "GeneCombination", "id": "651" }, { "type": "GeneCombination", "id": "654" }, { "type": "GeneCombination", "id": "655" }, { "type": "GeneCombination", "id": "665" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/PLXNB1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/PLXNB1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/PLXNB1/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }