Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/608/genes/?format=api
{ "data": [ { "type": "Gene", "id": "RASA1", "attributes": { "go_molecular_function": [ "GTPase binding", "potassium channel inhibitor activity", "protein binding", "signaling receptor binding", "phosphotyrosine residue binding" ], "pathway_id": [ "kegg_path:hsa04010", "R-HSA-5684996", "R-HSA-2682334", "R-HSA-4420097", "R-HSA-5218921", "R-HSA-162582", "R-HSA-5673001", "R-HSA-186797", "kegg_path:hsa04360", "R-HSA-186763", "R-HSA-8848021", "R-HSA-422475", "kegg_path:hsa04014", "R-HSA-194138", "R-HSA-5683057", "R-HSA-9675108", "R-HSA-9006927", "R-HSA-3928662", "R-HSA-1266738", "R-HSA-8849471", "R-HSA-9006934", "R-HSA-5658442" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P20936", "ensembl_id": "ENSG00000145715", "entrez_id": "5921", "chromosome_number": "5", "lastmodified": "2021-10-18T11:00:44.896357" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1836" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RASA1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RASA1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "608" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RASA1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RASA1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/RASA1/?format=api" } }, { "type": "Gene", "id": "TIMP3", "attributes": { "go_molecular_function": [ "protease binding", "protein binding", "metalloendopeptidase inhibitor activity" ], "pathway_id": [ "R-HSA-76005", "R-HSA-76002", "R-HSA-114608", "R-HSA-109582", "kegg_path:hsa05205", "kegg_path:hsa05206" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "P35625", "ensembl_id": "ENSG00000100234", "entrez_id": "7078", "chromosome_number": "22", "lastmodified": "2021-10-18T11:00:44.304608" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1837" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TIMP3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TIMP3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "608" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/TIMP3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/TIMP3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/TIMP3/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }