Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/607/genes/?format=api
{ "data": [ { "type": "Gene", "id": "ENG", "attributes": { "go_molecular_function": [ "protein binding", "transforming growth factor beta binding", "type II transforming growth factor beta receptor binding", "transforming growth factor beta-activated receptor activity", "glycosaminoglycan binding", "identical protein binding" ], "pathway_id": [], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "P17813", "ensembl_id": "ENSG00000106991", "entrez_id": "2022", "chromosome_number": "9", "lastmodified": "2021-10-18T11:00:44.664300" }, "relationships": { "variant_set": { "meta": { "count": 2 }, "data": [ { "type": "SmallVariant", "id": "1834" }, { "type": "SmallVariant", "id": "1838" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ENG/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ENG/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 2 }, "data": [ { "type": "GeneCombination", "id": "607" }, { "type": "GeneCombination", "id": "609" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/ENG/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/ENG/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/ENG/?format=api" } }, { "type": "Gene", "id": "MAP4K4", "attributes": { "go_molecular_function": [ "protein binding", "kinase activity", "protein serine/threonine kinase activity", "ATP binding", "microtubule binding", "creatine kinase activity" ], "pathway_id": [ "R-HSA-2559580", "R-HSA-2262752", "kegg_path:hsa04010", "R-HSA-8953897", "R-HSA-2559583" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "O95819", "ensembl_id": "ENSG00000071054", "entrez_id": "9448", "chromosome_number": "2", "lastmodified": "2021-10-18T11:00:44.936786" }, "relationships": { "variant_set": { "meta": { "count": 1 }, "data": [ { "type": "SmallVariant", "id": "1835" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAP4K4/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAP4K4/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 1 }, "data": [ { "type": "GeneCombination", "id": "607" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAP4K4/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAP4K4/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MAP4K4/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 2 } }